node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDK11A | HKR1 | ENSP00000384442 | ENSP00000315505 | Cyclin dependent kinase 11A | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.451 |
FAM110A | HKR1 | ENSP00000354163 | ENSP00000315505 | Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.478 |
GPATCH1 | GPR135 | ENSP00000170564 | ENSP00000378548 | G-patch domain containing 1; Belongs to the GPATCH1 family | Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.440 |
GPATCH1 | HKR1 | ENSP00000170564 | ENSP00000315505 | G-patch domain containing 1; Belongs to the GPATCH1 family | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.441 |
GPR135 | GPATCH1 | ENSP00000378548 | ENSP00000170564 | Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans | G-patch domain containing 1; Belongs to the GPATCH1 family | 0.440 |
GPR135 | HKR1 | ENSP00000378548 | ENSP00000315505 | Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.517 |
HEATR5B | HKR1 | ENSP00000233099 | ENSP00000315505 | HEAT repeat-containing protein 5B; Armadillo-like helical domain containing | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.455 |
HEATR5B | PLEKHH3 | ENSP00000233099 | ENSP00000468678 | HEAT repeat-containing protein 5B; Armadillo-like helical domain containing | Pleckstrin homology, MyTH4 and FERM domain containing H3 | 0.571 |
HKR1 | CDK11A | ENSP00000315505 | ENSP00000384442 | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Cyclin dependent kinase 11A | 0.451 |
HKR1 | FAM110A | ENSP00000315505 | ENSP00000354163 | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family | 0.478 |
HKR1 | GPATCH1 | ENSP00000315505 | ENSP00000170564 | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | G-patch domain containing 1; Belongs to the GPATCH1 family | 0.441 |
HKR1 | GPR135 | ENSP00000315505 | ENSP00000378548 | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Probable G-protein coupled receptor 135; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.517 |
HKR1 | HEATR5B | ENSP00000315505 | ENSP00000233099 | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | HEAT repeat-containing protein 5B; Armadillo-like helical domain containing | 0.455 |
HKR1 | MYCL | ENSP00000315505 | ENSP00000380494 | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Protein L-Myc; MYCL proto-oncogene, bHLH transcription factor; Basic helix-loop-helix proteins | 0.470 |
HKR1 | NRAS | ENSP00000315505 | ENSP00000358548 | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity | 0.523 |
HKR1 | PLEKHH3 | ENSP00000315505 | ENSP00000468678 | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Pleckstrin homology, MyTH4 and FERM domain containing H3 | 0.488 |
HKR1 | RNF103 | ENSP00000315505 | ENSP00000237455 | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | E3 ubiquitin-protein ligase RNF103; Acts as an E2-dependent E3 ubiquitin-protein ligase, probably involved in the ER-associated protein degradation pathway; Ring finger proteins | 0.519 |
HKR1 | TRIM28 | ENSP00000315505 | ENSP00000253024 | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.904 |
MYCL | HKR1 | ENSP00000380494 | ENSP00000315505 | Protein L-Myc; MYCL proto-oncogene, bHLH transcription factor; Basic helix-loop-helix proteins | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.470 |
NRAS | HKR1 | ENSP00000358548 | ENSP00000315505 | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity | Krueppel-related zinc finger protein 1; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.523 |