• Version:
  • 11.0 [archived version]
STRINGSTRING
ZNF431 ZNF431 C2orf61 C2orf61 LRRIQ4 LRRIQ4 ZNF28 ZNF28 KIAA1671 KIAA1671 CREG2 CREG2 ZNF430 ZNF430 ZNF708 ZNF708 LRRC10B LRRC10B FAM153C FAM153C C3orf70 C3orf70
"CREG2" - Protein CREG2 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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[Homology]
Score
CREG2Protein CREG2; Cellular repressor of E1A stimulated genes 2 (290 aa)    
Predicted Functional Partners:
C2orf61
Protein STPG4; Maternal factor that plays a role in epigenetic chromatin reprogramming during early development of the zygote. Involved in the regulation of gametic DNA demethylation by inducing the conversion of the modified genomic base 5- methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) (248 aa)
           
  0.622
ZNF28
Zinc finger protein 28; May be involved in transcriptional regulation; Zinc fingers C2H2-type (718 aa)
           
  0.543
FAM153C
Protein FAM153C; Family with sequence similarity 153 member C; Belongs to the FAM153 family (114 aa)
     
   
  0.539
C3orf70
UPF0524 protein C3orf70; Chromosome 3 open reading frame 70; Belongs to the UPF0524 family (250 aa)
           
  0.536
LRRIQ4
Leucine rich repeats and IQ motif containing 4 (560 aa)
           
  0.514
LRRC10B
Leucine-rich repeat-containing protein 10B; Leucine rich repeat containing 10B (292 aa)
           
  0.511
KIAA1671
Uncharacterized protein KIAA1671; KIAA1671 (1806 aa)
           
  0.511
ZNF431
Zinc finger protein 431; Sequence-specific DNA binding transcriptional repressor. Represses target gene transcription by recruiting HDAC1 and HDAC2 histone deacetylases. Acts as a specific transcriptional repressor for PTCH1 during embryonic development. Required for osteoblast differentiation and sonic hedgehog/SHH signaling response. Binds to the consensus site 5’-GCGCCC-3’ in the promoter of PTCH1 (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family (576 aa)
           
  0.511
ZNF708
Zinc finger protein 708; May be involved in transcriptional regulation; Zinc fingers C2H2-type (563 aa)
           
  0.510
ZNF430
Zinc finger protein 430; May be involved in transcriptional regulation; Zinc fingers C2H2-type (570 aa)
           
  0.497
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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