• Version:
  • 11.0 [archived version]
STRINGSTRING
HSPA1B HSPA1B LSMEM1 LSMEM1 OSER1 OSER1 ZFAND2A ZFAND2A ZFAND4 ZFAND4 ZZEF1 ZZEF1 WDR54 WDR54 PSMD7 PSMD7 UBB UBB CCDC140 CCDC140 PSMD1 PSMD1
"ZFAND2A" - Zinc finger AN1-type containing 2A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZFAND2AZinc finger AN1-type containing 2A (145 aa)    
Predicted Functional Partners:
OSER1
Oxidative stress-responsive serine-rich protein 1; Oxidative stress responsive serine rich 1 (292 aa)
     
   
  0.755
ZFAND4
Zinc finger AN1-type containing 4 (727 aa)
     
 
  0.585
PSMD7
26S proteasome non-ATPase regulatory subunit 7; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the peptidase M67A family (324 aa)
     
 
  0.583
WDR54
WD repeat-containing protein 54; WD repeat domain containing (334 aa)
           
  0.523
UBB
Polyubiquitin-B; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be involved in DNA repair; [...] (229 aa)
     
 
  0.483
HSPA1B
Heat shock protein family A member 1B (641 aa)
     
 
  0.483
CCDC140
Coiled-coil domain containing 140 (163 aa)
           
  0.473
PSMD1
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family (953 aa)
       
 
  0.467
LSMEM1
Leucine rich single-pass membrane protein 1 (131 aa)
           
  0.457
ZZEF1
Zinc finger ZZ-type and EF-hand domain containing 1 (2961 aa)
     
   
  0.448
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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