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STRINGSTRING
RNF17 RNF17 FIBP FIBP PARP4 PARP4 INTS8 INTS8 KIAA0195 KIAA0195 SLC25A42 SLC25A42 DEPDC1B DEPDC1B TMEM161A TMEM161A CASKIN2 CASKIN2 RSBN1 RSBN1 GPR84 GPR84
"KIAA0195" - Transmembrane protein 94 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
KIAA0195Transmembrane protein 94; KIAA0195 (1356 aa)    
Predicted Functional Partners:
FIBP
Acidic fibroblast growth factor intracellular-binding protein; May be involved in mitogenic function of FGF1. May mediate with IER2 FGF-signaling in the establishment of laterality in the embryo (By similarity) (364 aa)
        
      0.816
SLC25A42
Mitochondrial coenzyme A transporter SLC25A42; Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3’,5’- diphosphate; Solute carriers (318 aa)
      
   
  0.776
TMEM161A
Transmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis; Belongs to the TMEM161 family (479 aa)
            
  0.775
CASKIN2
Caskin-2; Sterile alpha motif domain containing (1202 aa)
      
   
  0.760
RNF17
RING finger protein 17; Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad- MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis (By similarity); Ring finger proteins (1623 aa)
            
  0.702
DEPDC1B
DEP domain containing 1B (529 aa)
            
  0.700
INTS8
Integrator complex subunit 8; Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3’-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (995 aa)
            
  0.692
GPR84
G-protein coupled receptor 84; Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10-0), undecanoic acid (C11-0) and lauric acid (C12-0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system (396 aa)
            
  0.619
PARP4
poly(ADP-ribose) polymerase family member 4 (1724 aa)
      
   
  0.537
RSBN1
Lysine-specific demethylase 9; Histone demethylase that specifically demethylates dimethylated ’Lys-20’ of histone H4 (H4K20me2), thereby modulating chromosome architecture; Belongs to the round spermatid basic protein 1 family (802 aa)
            
  0.535
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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