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KCNRG KCNRG KCNH6 KCNH6 SLC24A3 SLC24A3 KCNK2 KCNK2 KCNK10 KCNK10 KCNJ10 KCNJ10 KCNJ16 KCNJ16 PTPN21 PTPN21 EML5 EML5 EFCAB11 EFCAB11 GPR65 GPR65
"KCNK10" - Potassium channel subfamily K member 10 in Homo sapiens
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second shell of interactors
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some 3D structure is known or predicted
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textmining
co-expression
protein homology
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KCNK10Potassium channel subfamily K member 10; Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents. Activated by arachidonic acid and other naturally occurring unsaturated free fatty acids; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family (543 aa)    
Predicted Functional Partners:
KCNK2
Potassium channel subfamily K member 2; Ion channel that contributes to passive transmembrane potassium transport. Reversibly converts between a voltage-insensitive potassium leak channel and a voltage- dependent outward rectifying potassium channel in a phosphorylation-dependent manner. In astrocytes, forms mostly heterodimeric potassium channels with KCNK1, with only a minor proportion of functional channels containing homodimeric KCNK2. In astrocytes, the heterodimer formed by KCNK1 and KCNK2 is required for rapid glutamate release in response to activation of G-protein coupled rece [...] (426 aa)
         
0.808
SLC24A3
Sodium/potassium/calcium exchanger 3; Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+); Solute carriers (644 aa)
     
   
  0.647
KCNH6
Potassium voltage-gated channel subfamily H member 6; Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, rectifying current (By similarity). Channel properties may be modulated by cAMP and subunit assembly; Belongs to the potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.2/KCNH6 sub-subfamily (994 aa)
     
 
  0.610
KCNJ10
ATP-sensitive inward rectifier potassium channel 10; May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellu [...] (379 aa)
     
   
  0.529
KCNJ16
Inward rectifier potassium channel 16; Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance. In the kidney, together with KCNJ10, mediates basolater [...] (453 aa)
     
   
  0.504
EML5
Echinoderm microtubule-associated protein-like 5; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic; WD repeat domain containing (1977 aa)
     
   
  0.499
GPR65
Psychosine receptor; Receptor for the glycosphingolipid psychosine (PSY) and several related glycosphingolipids. Plays a role in immune response by maintaining lysosome function and supporting phagocytosis-mediated intracellular bacteria clearance. May have a role in activation-induced cell death or differentiation of T-cells (By similarity); G protein-coupled receptors, Class A orphans (337 aa)
       
 
  0.480
EFCAB11
EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11 (163 aa)
           
  0.479
KCNRG
Potassium channel regulatory protein; Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes (272 aa)
           
  0.473
PTPN21
Protein tyrosine phosphatase, non-receptor type 21; FERM domain containing (1174 aa)
           
  0.473
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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