• Version:
  • 11.0 [archived version]
STRINGSTRING
C20orf195 C20orf195 UBL4B UBL4B NT5DC2 NT5DC2 C11orf70 C11orf70 C2orf69 C2orf69 C8orf82 C8orf82 C15orf40 C15orf40 SPATS2L SPATS2L C2orf47 C2orf47 TYW5 TYW5 KCTD18 KCTD18
"C2orf69" - UPF0565 protein C2orf69 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C2orf69UPF0565 protein C2orf69; Chromosome 2 open reading frame 69 (385 aa)    
Predicted Functional Partners:
TYW5
tRNA wybutosine-synthesizing protein 5; tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3’-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes; Belongs to the TYW5 family (315 aa)
           
  0.609
C2orf47
m-AAA protease-interacting protein 1, mitochondrial; Promotes sorting of SMDT1/EMRE in mitochondria by ensuring its maturation. Interacts with the transit peptide region of SMDT1/EMRE precursor protein in the mitochondrial matrix, leading to protect it against protein degradation by YME1L1, thereby ensuring SMDT1/EMRE maturation by the mitochondrial processing peptidase (PMPCA and PMPCB) (291 aa)
           
  0.608
SPATS2L
SPATS2-like protein; Spermatogenesis associated serine rich 2 like; Belongs to the SPATS2 family (588 aa)
           
  0.599
C15orf40
UPF0235 protein C15orf40; Chromosome 15 open reading frame 40 (167 aa)
           
  0.590
NT5DC2
5’-nucleotidase domain containing 2 (557 aa)
     
   
  0.571
KCTD18
BTB/POZ domain-containing protein KCTD18; Potassium channel tetramerization domain containing 18 (426 aa)
     
   
  0.559
C8orf82
UPF0598 protein C8orf82; Chromosome 8 open reading frame 82 (216 aa)
           
  0.519
C11orf70
Uncharacterized protein C11orf70; Chromosome 11 open reading frame 70 (267 aa)
           
  0.518
UBL4B
Ubiquitin-like protein 4B; Ubiquitin like 4B (174 aa)
     
   
  0.504
C20orf195
Fibronectin type III domain-containing protein 11; Chromosome 20 open reading frame 195 (318 aa)
           
  0.495
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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