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  • 11.0 [archived version]
STRINGSTRING
ATXN7L2 ATXN7L2 GNPAT GNPAT TEX2 TEX2 JAG1 JAG1 ARV1 ARV1 PIGG PIGG ALG6 ALG6 ALG3 ALG3 ALG8 ALG8 ALG5 ALG5 ALG12 ALG12
"ARV1" - Protein ARV1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ARV1Protein ARV1; Plays a role as a mediator in the endoplasmic reticulum (ER) cholesterol and bile acid homeostasis. Participates in sterol transport out of the ER and distribution into plasma membranes (271 aa)    
Predicted Functional Partners:
PIGG
GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose; Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily (983 aa)
     
 
  0.757
JAG1
Protein jagged-1; Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro); CD molecules (1218 aa)
           
  0.715
ALG12
Dol-P-Man-Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP- Man(7)GlcNAc(2)) required for protein glycosylation; Belongs to the glycosyltransferase 22 family (488 aa)
           
  0.711
ATXN7L2
Ataxin-7-like protein 2; Ataxin 7 like 2 (722 aa)
           
  0.706
ALG8
Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity); Alpha-1,3-glucosyltransferases (526 aa)
     
 
  0.701
ALG5
ALG5, dolichyl-phosphate beta-glucosyltransferase; Glycosyltransferase family 2 (324 aa)
     
   
  0.693
ALG3
Dol-P-Man-Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man5GlcNAc2-PP-Dol; Dolichyl D-mannosyl phosphate dependent mannosyltransferases (438 aa)
     
   
  0.686
TEX2
Testis-expressed protein 2; Testis expressed 2 (1134 aa)
           
  0.646
GNPAT
Glyceronephosphate O-acyltransferase (680 aa)
     
   
  0.646
ALG6
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol; Alpha-1,3-glucosyltransferases (507 aa)
     
 
  0.643
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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