• Version:
  • 11.0 [archived version]
STRINGSTRING
MAGEB2 MAGEB2 CTAG1B CTAG1B CTAG1A CTAG1A ZNF83 ZNF83 MAGEB1 MAGEB1 SS18 SS18 SSX5 SSX5 ZNF117 ZNF117 SSX2IP SSX2IP IGSF22 IGSF22 SPANXN1 SPANXN1
"SSX5" - Synovial sarcoma, X breakpoint 5 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
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[Homology]
Score
SSX5Synovial sarcoma, X breakpoint 5; SSX family member 5 (229 aa)    
Predicted Functional Partners:
ZNF117
Zinc finger protein 117; May be involved in transcriptional regulation; Zinc fingers C2H2-type (483 aa)
           
  0.710
SS18
Protein SSXT; Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation; BAF complex (418 aa)
           
  0.662
ZNF83
Zinc finger protein 83; May be involved in transcriptional regulation; Zinc fingers C2H2-type (516 aa)
           
  0.648
SSX2IP
Afadin- and alpha-actinin-binding protein; Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E- cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity). Involved in cell movement- localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via a [...] (614 aa)
           
  0.595
MAGEB2
Melanoma-associated antigen B2; May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3-substrate complex; MAGE family (319 aa)
           
  0.572
MAGEB1
Melanoma-associated antigen B1; MAGE family member B1 (347 aa)
           
  0.560
CTAG1A
Cancer/testis antigen 1A; Belongs to the CTAG/PCC1 family (180 aa)
           
  0.530
IGSF22
Immunoglobulin superfamily, member 22; Fibronectin type III domain containing (1326 aa)
           
  0.530
SPANXN1
Sperm protein associated with the nucleus on the X chromosome N1; SPANX family member N1; Belongs to the SPAN-X family (72 aa)
           
  0.530
CTAG1B
Cancer/testis antigen 1B; Belongs to the CTAG/PCC1 family (180 aa)
           
  0.529
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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