• Version:
  • 11.0 [archived version]
STRINGSTRING
HEATR5A HEATR5A DTD1 DTD1 YARS YARS YARS2 YARS2 UBBP4 UBBP4 DTD2 DTD2 POTEC POTEC SLC35G6 SLC35G6 RBM42 RBM42 ERP29 ERP29 TMEM9 TMEM9
"DTD2" - Putative D-tyrosyl-tRNA(Tyr) deacylase 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DTD2Putative D-tyrosyl-tRNA(Tyr) deacylase 2; May D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (Potential) (168 aa)    
Predicted Functional Partners:
YARS
Tyrosine--tRNA ligase, cytoplasmic; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family (528 aa)
   
   
  0.754
DTD1
D-aminoacyl-tRNA deacylase 1; Possible ATPase involved in DNA replication, may facilitate loading of CDC45 onto pre-replication complexes (209 aa)
           
  0.732
RBM42
RNA-binding protein 42; Binds (via the RRM domain) to the 3’-untranslated region (UTR) of CDKN1A mRNA; RNA binding motif containing (480 aa)
           
  0.724
TMEM9
Transmembrane protein 9; May be involved in intracellular transport (186 aa)
           
  0.700
YARS2
Tyrosine--tRNA ligase, mitochondrial; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family (477 aa)
   
   
  0.604
SLC35G6
Solute carrier family 35 member G6 (338 aa)
           
  0.537
POTEC
POTE ankyrin domain family member C (542 aa)
           
  0.533
UBBP4
Ubiquitin B pseudogene 4 (229 aa)
           
  0.532
HEATR5A
HEAT repeat-containing protein 5A; Armadillo-like helical domain containing (2046 aa)
           
  0.530
ERP29
Endoplasmic reticulum resident protein 29; Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER (261 aa)
           
  0.522
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (0%) [HD]