BTN2A1 protein (human) - STRING database

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BTN2A1

Butyrophilin subfamily 2 member A1; Butyrophilins (527 aa)

Predicted Functional Partners:

CD209

0.932

SLC4A11

0.474

FAM78B

0.452

LRFN5

0.442

ZNF205

0.430

SPSB3

0.428

BCLAF1

0.426

SVOP

0.424

POM121L2

0.410

XDH

0.409

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCLAF1	BTN2A1	ENSP00000435210	ENSP00000312158	Bcl-2-associated transcription factor 1; Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3’end of the CCND1 gene and its mRNA	Butyrophilin subfamily 2 member A1; Butyrophilins	0.426
BTN2A1	BCLAF1	ENSP00000312158	ENSP00000435210	Butyrophilin subfamily 2 member A1; Butyrophilins	Bcl-2-associated transcription factor 1; Death-promoting transcriptional repressor. May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3’end of the CCND1 gene and its mRNA	0.426
BTN2A1	CD209	ENSP00000312158	ENSP00000315477	Butyrophilin subfamily 2 member A1; Butyrophilins	CD209 antigen; Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response; C-type lectin domain containing	0.932
BTN2A1	FAM78B	ENSP00000312158	ENSP00000339681	Butyrophilin subfamily 2 member A1; Butyrophilins	Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family	0.452
BTN2A1	LRFN5	ENSP00000312158	ENSP00000298119	Butyrophilin subfamily 2 member A1; Butyrophilins	Leucine-rich repeat and fibronectin type-III domain-containing protein 5; Cell adhesion molecule that mediates homophilic cell- cell adhesion in a Ca(2+)-independent manner. Promotes neurite outgrowth in hippocampal neurons; Belongs to the LRFN family	0.442
BTN2A1	POM121L2	ENSP00000312158	ENSP00000392726	Butyrophilin subfamily 2 member A1; Butyrophilins	POM121-like protein 2; POM121 transmembrane nucleoporin like 2; Belongs to the POM121 family	0.410
BTN2A1	SLC4A11	ENSP00000312158	ENSP00000369399	Butyrophilin subfamily 2 member A1; Butyrophilins	Sodium bicarbonate transporter-like protein 11; Transporter which plays an important role in sodium- mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sodium flux into t [...]	0.474
BTN2A1	SPSB3	ENSP00000312158	ENSP00000457206	Butyrophilin subfamily 2 member A1; Butyrophilins	SPRY domain-containing SOCS box protein 3; May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins	0.428
BTN2A1	SVOP	ENSP00000312158	ENSP00000479104	Butyrophilin subfamily 2 member A1; Butyrophilins	Synaptic vesicle 2-related protein; SV2 related protein	0.424
BTN2A1	XDH	ENSP00000312158	ENSP00000368727	Butyrophilin subfamily 2 member A1; Butyrophilins	Xanthine dehydrogenase/oxidase; Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro)	0.409
BTN2A1	ZNF205	ENSP00000312158	ENSP00000480401	Butyrophilin subfamily 2 member A1; Butyrophilins	Zinc finger protein 205; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.430
CD209	BTN2A1	ENSP00000315477	ENSP00000312158	CD209 antigen; Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response; C-type lectin domain containing	Butyrophilin subfamily 2 member A1; Butyrophilins	0.932
FAM78B	BTN2A1	ENSP00000339681	ENSP00000312158	Protein FAM78B; Family with sequence similarity 78 member B; Belongs to the FAM78 family	Butyrophilin subfamily 2 member A1; Butyrophilins	0.452
LRFN5	BTN2A1	ENSP00000298119	ENSP00000312158	Leucine-rich repeat and fibronectin type-III domain-containing protein 5; Cell adhesion molecule that mediates homophilic cell- cell adhesion in a Ca(2+)-independent manner. Promotes neurite outgrowth in hippocampal neurons; Belongs to the LRFN family	Butyrophilin subfamily 2 member A1; Butyrophilins	0.442
POM121L2	BTN2A1	ENSP00000392726	ENSP00000312158	POM121-like protein 2; POM121 transmembrane nucleoporin like 2; Belongs to the POM121 family	Butyrophilin subfamily 2 member A1; Butyrophilins	0.410
SLC4A11	BTN2A1	ENSP00000369399	ENSP00000312158	Sodium bicarbonate transporter-like protein 11; Transporter which plays an important role in sodium- mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sodium flux into t [...]	Butyrophilin subfamily 2 member A1; Butyrophilins	0.474
SPSB3	BTN2A1	ENSP00000457206	ENSP00000312158	SPRY domain-containing SOCS box protein 3; May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins	Butyrophilin subfamily 2 member A1; Butyrophilins	0.428
SVOP	BTN2A1	ENSP00000479104	ENSP00000312158	Synaptic vesicle 2-related protein; SV2 related protein	Butyrophilin subfamily 2 member A1; Butyrophilins	0.424
SVOP	ZNF205	ENSP00000479104	ENSP00000480401	Synaptic vesicle 2-related protein; SV2 related protein	Zinc finger protein 205; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family	0.441
XDH	BTN2A1	ENSP00000368727	ENSP00000312158	Xanthine dehydrogenase/oxidase; Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro)	Butyrophilin subfamily 2 member A1; Butyrophilins	0.409

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