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STRINGSTRING
C19orf47 C19orf47 ZNF780A ZNF780A IRGQ IRGQ ATP5SL ATP5SL HIPK4 HIPK4 DNAJC7 DNAJC7 TULP2 TULP2 TTC9B TTC9B RTBDN RTBDN FBXL16 FBXL16 HP1BP3 HP1BP3
"TTC9B" - Tetratricopeptide repeat domain containing in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TTC9BTetratricopeptide repeat domain containing (239 aa)    
Predicted Functional Partners:
HP1BP3
Heterochromatin protein 1-binding protein 3; Component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity. Mediates chromatin condensation during hypoxia, leading to increased tumor cell viability, radio-resistance, chemo-resistance and self- renewal (553 aa)
            
  0.668
ATP5SL
Distal membrane-arm assembly complex protein 2; Required for the assembly of the mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). Involved in the assembly of the distal region of complex I; Belongs to the ATP synthase subunit s family (263 aa)
            
  0.621
HIPK4
Homeodomain-interacting protein kinase 4; Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter (By similarity). May act as a corepressor of transcription factors (Potential) (616 aa)
      
   
  0.600
FBXL16
F-box/LRR-repeat protein 16; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and leucine rich repeat proteins (479 aa)
      
   
  0.600
RTBDN
Retbindin; Riboflavin-binding protein which might have a role in retinal flavin transport (261 aa)
      
   
  0.584
IRGQ
Immunity-related GTPase family Q protein; Immunity related GTPase Q; Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family (623 aa)
      
   
  0.584
DNAJC7
DnaJ homolog subfamily C member 7; Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone- substrate complexes. Recruits NR1I3 to the cytoplasm (By similarity); DNAJ heat shock proteins (494 aa)
            
  0.566
ZNF780A
Zinc finger protein 780A; May be involved in transcriptional regulation; Zinc fingers C2H2-type (642 aa)
            
  0.545
C19orf47
Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47 (422 aa)
            
  0.535
TULP2
Tubby like protein 2; Belongs to the TUB family (520 aa)
      
   
  0.532
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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