• Version:
  • 11.0 [archived version]
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KIAA1328 KIAA1328 C7orf43 C7orf43 ANKRD13C ANKRD13C GRIP2 GRIP2 OR8D2 OR8D2 ZNF417 ZNF417 LRRC66 LRRC66 TRIM28 TRIM28 ZFAND4 ZFAND4 CLHC1 CLHC1 TIGD3 TIGD3
"ZNF417" - Zinc finger protein 417 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
Coexpression
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[Homology]
Score
ZNF417Zinc finger protein 417; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (575 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
  0.906
OR8D2
Olfactory receptor 8D2; Odorant receptor (Potential). May be involved in taste perception; Olfactory receptors, family 8 (311 aa)
           
  0.555
CLHC1
Clathrin heavy chain linker domain containing 1 (586 aa)
     
   
  0.545
TIGD3
Tigger transposable element-derived protein 3; Helix-turn-helix CENPB type domain containing; DNA transposon derived genes (471 aa)
       
 
  0.523
LRRC66
Leucine-rich repeat-containing protein 66; Leucine rich repeat containing 66 (880 aa)
       
 
  0.523
ZFAND4
Zinc finger AN1-type containing 4 (727 aa)
     
 
  0.515
GRIP2
Glutamate receptor-interacting protein 2; May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons; PDZ domain containing (1140 aa)
       
 
  0.459
KIAA1328
Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes (577 aa)
     
   
  0.454
ANKRD13C
Ankyrin repeat domain-containing protein 13C; Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER; Ankyrin repeat domain containing (541 aa)
           
  0.450
C7orf43
Uncharacterized protein C7orf43; Chromosome 7 open reading frame 43 (580 aa)
           
  0.448
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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