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  • 11.0 [archived version]
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UTP3 UTP3 NOP14 NOP14 NOC4L NOC4L BMS1 BMS1 UTP14A UTP14A UTP14C UTP14C DDX49 DDX49 MPHOSPH10 MPHOSPH10 CIRH1A CIRH1A DHX37 DHX37 NOL6 NOL6
"DHX37" - Probable ATP-dependent RNA helicase DHX37 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
DHX37Probable ATP-dependent RNA helicase DHX37; DEAH-box helicase 37 (1157 aa)    
Predicted Functional Partners:
UTP14A
U3 small nucleolar RNA-associated protein 14 homolog A; May be required for ribosome biogenesis (771 aa)
     
  0.998
NOL6
Nucleolar protein 6; Belongs to the NRAP family (1146 aa)
     
  0.997
DDX49
Probable ATP-dependent RNA helicase DDX49; DEAD-box helicase 49; Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily (483 aa)
     
  0.997
MPHOSPH10
U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; MPP10 subcomplex (681 aa)
     
  0.997
NOC4L
Nucleolar complex protein 4 homolog; Armadillo-like helical domain containing; Belongs to the CBF/MAK21 family (516 aa)
     
  0.997
CIRH1A
U3 small nucleolar RNA-associated protein 4 homolog; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in small subunit (SSU) pre-rRNA processing at sites A’, A0, 1 and 2b. Required for optimal pre-ribosomal RNA transcription by RNA polymerase. May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5’-GGGACTTTCC-3’ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV (686 aa)
     
  0.997
NOP14
Nucleolar protein 14; Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity); Belongs to the NOP14 family (857 aa)
     
  0.996
UTP14C
U3 small nucleolar RNA-associated protein 14 homolog C; Essential for spermatogenesis. May be required specifically for ribosome biogenesis and hence protein synthesis during male meiosis (By similarity) (766 aa)
     
  0.996
UTP3
Something about silencing protein 10; Essential for gene silencing- has a role in the structure of silenced chromatin. Plays a role in the developing brain (By similarity); Belongs to the SAS10 family (479 aa)
     
  0.996
BMS1
Ribosome biogenesis protein BMS1 homolog; May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (1282 aa)
     
  0.995
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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