• Version:
  • 11.0 [archived version]
STRINGSTRING
GPR89B GPR89B CHP1 CHP1 GLIS3 GLIS3 DECR1 DECR1 GPR171 GPR171 GPR152 GPR152 SPX SPX GPR162 GPR162 GPR82 GPR82 C11orf24 C11orf24 GPR89A GPR89A
"GPR152" - Probable G-protein coupled receptor 152 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR152Probable G-protein coupled receptor 152; Orphan receptor; G protein-coupled receptors, Class A orphans (470 aa)    
Predicted Functional Partners:
GLIS3
Zinc finger protein GLIS3; Acts as both a repressor and activator of transcription. Binds to the consensus sequence 5’-GACCACCCAC-3’ (By similarity); Zinc fingers C2H2-type (930 aa)
           
  0.793
SPX
Spexin; Plays a role as a central modulator of cardiovascular and renal function and nociception. Plays also a role in energy metabolism and storage. Inhibits adrenocortical cell proliferation with minor stimulation on corticosteroid release (By similarity) (116 aa)
           
  0.709
GPR89A
G protein-coupled receptor 89A; Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance; Belongs to the Golgi pH regulator (TC 1.A.38) family (455 aa)
           
  0.458
GPR171
Probable G-protein coupled receptor 171; Orphan receptor; G protein-coupled receptors, Class A orphans (319 aa)
           
  0.457
GPR89B
Golgi pH regulator A; Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance; Belongs to the Golgi pH regulator (TC 1.A.38) family (455 aa)
           
  0.453
C11orf24
Uncharacterized protein C11orf24; Chromosome 11 open reading frame 24 (449 aa)
           
  0.453
GPR162
Probable G-protein coupled receptor 162; Orphan receptor; G protein-coupled receptors, Class A orphans (588 aa)
           
  0.446
DECR1
2,4-dienoyl-CoA reductase, mitochondrial; Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA; Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily (335 aa)
           
  0.442
CHP1
Calcineurin B homologous protein 1; Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exc [...] (195 aa)
           
  0.441
GPR82
Probable G-protein coupled receptor 82; Orphan receptor; G protein-coupled receptors, Class A orphans (336 aa)
           
  0.437
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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