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  • 11.0 [archived version]
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SLC15A1 SLC15A1 SLC17A3 SLC17A3 SLC17A1 SLC17A1 SLC19A1 SLC19A1 SLC47A1 SLC47A1 SLC2A9 SLC2A9 SLC22A13 SLC22A13 SLC2A8 SLC2A8 OXSR1 OXSR1 FUCA2 FUCA2 XYLB XYLB
"SLC22A13" - Solute carrier family 22 member 13 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
SLC22A13Solute carrier family 22 member 13 (551 aa)    
Predicted Functional Partners:
XYLB
Xylulose kinase; Phosphorylates D-xylulose to produce D-xylulose 5- phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis (536 aa)
     
   
  0.911
OXSR1
Serine/threonine-protein kinase OSR1; Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily (527 aa)
           
  0.806
SLC2A9
Solute carrier family 2, facilitated glucose transporter member 9; Transport urate and fructose. May have a role in the urate reabsorption by proximal tubules. Also transports glucose at low rate; Solute carriers (540 aa)
   
 
  0.745
SLC15A1
Solute carrier family 15 member 1; Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. May constitute a major route for the absorption of protein digestion end-products; Solute carriers (708 aa)
     
   
  0.743
SLC17A3
Sodium-dependent phosphate transport protein 4; Isoform 2- voltage-driven, multispecific, organic anion transporter able to transport para-aminohippurate (PAH), estrone sulfate, estradiol-17-beta-glucuronide, bumetanide, and ochratoxin A. Isoform 2 functions as urate efflux transporter on the apical side of renal proximal tubule and is likely to act as an exit path for organic anionic drugs as well as urate in vivo. May be involved in actively transporting phosphate into cells via Na(+) cotransport; Belongs to the major facilitator superfamily. Sodium/anion cotransporter family (498 aa)
   
     
  0.725
FUCA2
Plasma alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N- acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family (467 aa)
           
  0.676
SLC19A1
Folate transporter 1; Transporter for the intake of folate. Uptake of folate in human placental choriocarcinoma cells occurs by a novel mechanism called potocytosis which functionally couples three components, namely the folate receptor, the folate transporter, and a V-type H(+)-pump; Minor histocompatibility antigens (591 aa)
           
  0.674
SLC17A1
Sodium-dependent phosphate transport protein 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Plays a role in urate transport in the kidney; Solute carriers (467 aa)
           
  0.672
SLC47A1
Multidrug and toxin extrusion protein 1; Solute transporter for tetraethylammonium (TEA), 1- methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4’-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes (570 aa)
     
   
  0.668
SLC2A8
Solute carrier family 2, facilitated glucose transporter member 8; Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose (By similarity); Solute carriers (477 aa)
   
 
 
  0.662
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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