node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BSG | SLC16A13 | ENSP00000333769 | ENSP00000309751 | Basigin; Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3, SLC16A8 and SLC16A11 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes; Blood group antigens | Monocarboxylate transporter 13; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane; Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family | 0.853 |
C2CD4A | SLC16A13 | ENSP00000347712 | ENSP00000309751 | C2 calcium-dependent domain-containing protein 4A; May be involved in inflammatory process. May regulate cell architecture and adhesion; Belongs to the C2CD4 family | Monocarboxylate transporter 13; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane; Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family | 0.441 |
FRYL | SLC16A13 | ENSP00000351113 | ENSP00000309751 | Protein furry homolog-like; Plays a key role in maintaining the integrity of polarized cell extensions during morphogenesis, regulates the actin cytoskeleton and plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by limiting dendritic branching (By similarity). May function as a transcriptional activator; Belongs to the furry protein family | Monocarboxylate transporter 13; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane; Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family | 0.509 |
GPSM1 | SLC16A13 | ENSP00000392828 | ENSP00000309751 | G-protein-signaling modulator 1; Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction; Belongs to the GPSM family | Monocarboxylate transporter 13; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane; Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family | 0.583 |
HSD3B1 | SLC16A13 | ENSP00000358421 | ENSP00000309751 | 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17- alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta,17 beta-diol, dehydroepiandrosterone to [...] | Monocarboxylate transporter 13; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane; Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family | 0.783 |
SLC16A13 | BSG | ENSP00000309751 | ENSP00000333769 | Monocarboxylate transporter 13; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane; Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family | Basigin; Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3, SLC16A8 and SLC16A11 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes; Blood group antigens | 0.853 |
SLC16A13 | C2CD4A | ENSP00000309751 | ENSP00000347712 | Monocarboxylate transporter 13; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane; Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family | C2 calcium-dependent domain-containing protein 4A; May be involved in inflammatory process. May regulate cell architecture and adhesion; Belongs to the C2CD4 family | 0.441 |
SLC16A13 | FRYL | ENSP00000309751 | ENSP00000351113 | Monocarboxylate transporter 13; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane; Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family | Protein furry homolog-like; Plays a key role in maintaining the integrity of polarized cell extensions during morphogenesis, regulates the actin cytoskeleton and plays a key role in patterning sensory neuron dendritic fields by promoting avoidance between homologous dendrites as well as by limiting dendritic branching (By similarity). May function as a transcriptional activator; Belongs to the furry protein family | 0.509 |
SLC16A13 | GPSM1 | ENSP00000309751 | ENSP00000392828 | Monocarboxylate transporter 13; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane; Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family | G-protein-signaling modulator 1; Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G- protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction; Belongs to the GPSM family | 0.583 |
SLC16A13 | HSD3B1 | ENSP00000309751 | ENSP00000358421 | Monocarboxylate transporter 13; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane; Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family | 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1; 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17- alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta,17 beta-diol, dehydroepiandrosterone to [...] | 0.783 |
SLC16A13 | SLC25A30 | ENSP00000309751 | ENSP00000429168 | Monocarboxylate transporter 13; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane; Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family | Kidney mitochondrial carrier protein 1; Probable transporter; Belongs to the mitochondrial carrier (TC 2.A.29) family | 0.413 |
SLC25A30 | SLC16A13 | ENSP00000429168 | ENSP00000309751 | Kidney mitochondrial carrier protein 1; Probable transporter; Belongs to the mitochondrial carrier (TC 2.A.29) family | Monocarboxylate transporter 13; Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane; Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family | 0.413 |