• Version:
  • 11.0 [archived version]
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CNOT6L CNOT6L UGDH UGDH LUZP2 LUZP2 QRFPR QRFPR KLHL8 KLHL8 NKAIN3 NKAIN3 TRAM1L1 TRAM1L1 FAM174A FAM174A SSR3 SSR3 SSR2 SSR2 NDST4 NDST4
"TRAM1L1" - Translocating chain-associated membrane protein 1-like 1 in Homo sapiens
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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TRAM1L1Translocating chain-associated membrane protein 1-like 1; Stimulatory or required for the translocation of secretory proteins across the ER membrane; TLC domain containing (369 aa)    
Predicted Functional Partners:
QRFPR
Pyroglutamylated RFamide peptide receptor; Receptor for the orexigenic neuropeptide QRFP. The activity of this receptor is mediated by G proteins that modulate adenylate cyclase activity and intracellular calcium levels (431 aa)
           
  0.702
CNOT6L
CCR4-NOT transcription complex subunit 6-like; Has 3’-5’ poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in the deadenylation-dependent degradation of mRNAs through the 3’ [...] (555 aa)
           
  0.674
KLHL8
Kelch-like protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN; BTB domain containing (620 aa)
       
 
  0.654
UGDH
UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate (494 aa)
     
   
  0.642
SSR2
Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins; Belongs to the TRAP-beta family (183 aa)
     
        0.621
SSR3
Translocon-associated protein subunit gamma; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins; Belongs to the TRAP-gamma family (185 aa)
     
   
  0.620
NKAIN3
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3; Sodium/potassium transporting ATPase interacting 3; Belongs to the NKAIN family (197 aa)
     
   
  0.592
FAM174A
Membrane protein FAM174A; Family with sequence similarity 174 member A (190 aa)
           
  0.560
NDST4
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4; Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has low deacetylase activity but high sulfotransferase activity (By similarity); Belongs to the sulfotransferase 1 family. NDST subfamily (872 aa)
           
  0.511
LUZP2
Leucine zipper protein 2 (346 aa)
     
   
  0.484
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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