ZNF680 protein (human) - STRING database

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ZNF680

Zinc finger protein 680; May be involved in transcriptional regulation; Zinc fingers C2H2-type (530 aa)

Predicted Functional Partners:

TRIM28

0.904

KIAA1841

0.567

MAP1S

0.552

POMK

0.519

HGSNAT

0.511

UBXN7

0.500

FSD1

0.486

COMMD6

0.477

FCRL6

0.471

ALPK2

0.453

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALPK2	UBXN7	ENSP00000354991	ENSP00000296328	Alpha-protein kinase 2; Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation; I-set domain containing	UBX domain-containing protein 7; Ubiquitin-binding adapter that links a subset of NEDD8- associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitination substrates; UBX domain containing	0.424
ALPK2	ZNF680	ENSP00000354991	ENSP00000309330	Alpha-protein kinase 2; Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation; I-set domain containing	Zinc finger protein 680; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.453
COMMD6	KIAA1841	ENSP00000348054	ENSP00000385579	COMM domain containing 6; CCC complex	Uncharacterized protein KIAA1841; KIAA1841	0.430
COMMD6	UBXN7	ENSP00000348054	ENSP00000296328	COMM domain containing 6; CCC complex	UBX domain-containing protein 7; Ubiquitin-binding adapter that links a subset of NEDD8- associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitination substrates; UBX domain containing	0.900
COMMD6	ZNF680	ENSP00000348054	ENSP00000309330	COMM domain containing 6; CCC complex	Zinc finger protein 680; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.477
FCRL6	KIAA1841	ENSP00000357086	ENSP00000385579	Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing	Uncharacterized protein KIAA1841; KIAA1841	0.416
FCRL6	ZNF680	ENSP00000357086	ENSP00000309330	Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing	Zinc finger protein 680; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.471
FSD1	UBXN7	ENSP00000221856	ENSP00000296328	Fibronectin type III and SPRY domain-containing protein 1; May be involved in microtubule organization and stabilization; Fibronectin type III domain containing	UBX domain-containing protein 7; Ubiquitin-binding adapter that links a subset of NEDD8- associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitination substrates; UBX domain containing	0.448
FSD1	ZNF680	ENSP00000221856	ENSP00000309330	Fibronectin type III and SPRY domain-containing protein 1; May be involved in microtubule organization and stabilization; Fibronectin type III domain containing	Zinc finger protein 680; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.486
HGSNAT	MAP1S	ENSP00000368965	ENSP00000325313	Heparan-alpha-glucosaminide N-acetyltransferase; Lysosomal acetyltransferase that acetylates the non- reducing terminal alpha-glucosamine residue of intralysosomal heparin or heparan sulfate, converting it into a substrate for luminal alpha-N-acetyl glucosaminidase	Microtubule-associated protein 1S; Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity); Belongs to the MAP1 family	0.568
HGSNAT	POMK	ENSP00000368965	ENSP00000331258	Heparan-alpha-glucosaminide N-acetyltransferase; Lysosomal acetyltransferase that acetylates the non- reducing terminal alpha-glucosamine residue of intralysosomal heparin or heparan sulfate, converting it into a substrate for luminal alpha-N-acetyl glucosaminidase	Protein O-mannose kinase; Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N- acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine- beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only [...]	0.792
HGSNAT	ZNF680	ENSP00000368965	ENSP00000309330	Heparan-alpha-glucosaminide N-acetyltransferase; Lysosomal acetyltransferase that acetylates the non- reducing terminal alpha-glucosamine residue of intralysosomal heparin or heparan sulfate, converting it into a substrate for luminal alpha-N-acetyl glucosaminidase	Zinc finger protein 680; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.511
KIAA1841	COMMD6	ENSP00000385579	ENSP00000348054	Uncharacterized protein KIAA1841; KIAA1841	COMM domain containing 6; CCC complex	0.430
KIAA1841	FCRL6	ENSP00000385579	ENSP00000357086	Uncharacterized protein KIAA1841; KIAA1841	Fc receptor-like protein 6; Acts as a MHC class II receptor. When stimulated on its own, does not play a role in cytokine production or the release of cytotoxic granules by NK cells and cytotoxic CD8(+) T cells. Does not act as an Fc receptor; Immunoglobulin like domain containing	0.416
KIAA1841	ZNF680	ENSP00000385579	ENSP00000309330	Uncharacterized protein KIAA1841; KIAA1841	Zinc finger protein 680; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.567
MAP1S	HGSNAT	ENSP00000325313	ENSP00000368965	Microtubule-associated protein 1S; Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity); Belongs to the MAP1 family	Heparan-alpha-glucosaminide N-acetyltransferase; Lysosomal acetyltransferase that acetylates the non- reducing terminal alpha-glucosamine residue of intralysosomal heparin or heparan sulfate, converting it into a substrate for luminal alpha-N-acetyl glucosaminidase	0.568
MAP1S	POMK	ENSP00000325313	ENSP00000331258	Microtubule-associated protein 1S; Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity); Belongs to the MAP1 family	Protein O-mannose kinase; Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N- acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine- beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only [...]	0.630
MAP1S	ZNF680	ENSP00000325313	ENSP00000309330	Microtubule-associated protein 1S; Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity); Belongs to the MAP1 family	Zinc finger protein 680; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.552
POMK	HGSNAT	ENSP00000331258	ENSP00000368965	Protein O-mannose kinase; Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N- acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine- beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only [...]	Heparan-alpha-glucosaminide N-acetyltransferase; Lysosomal acetyltransferase that acetylates the non- reducing terminal alpha-glucosamine residue of intralysosomal heparin or heparan sulfate, converting it into a substrate for luminal alpha-N-acetyl glucosaminidase	0.792
POMK	MAP1S	ENSP00000331258	ENSP00000325313	Protein O-mannose kinase; Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N- acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine- beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only [...]	Microtubule-associated protein 1S; Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity); Belongs to the MAP1 family	0.630

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