node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMZ1 | ZNF471 | ENSP00000308149 | ENSP00000309161 | Archaemetzincin-1; Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2; Belongs to the peptidase M54 family | Zinc finger protein 471; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.429 |
BAZ1A | ZNF471 | ENSP00000353458 | ENSP00000309161 | Bromodomain adjacent to zinc finger domain protein 1A; Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S pha [...] | Zinc finger protein 471; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.568 |
FOXB1 | SUSD5 | ENSP00000379369 | ENSP00000308727 | Forkhead box B1 | Sushi domain containing 5 | 0.420 |
FOXB1 | ZNF471 | ENSP00000379369 | ENSP00000309161 | Forkhead box B1 | Zinc finger protein 471; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.468 |
FOXD2 | SUSD5 | ENSP00000335493 | ENSP00000308727 | Forkhead box protein D2; Probable transcription factor involved in embryogenesis and somatogenesis; Forkhead boxes | Sushi domain containing 5 | 0.440 |
FOXD2 | ZNF471 | ENSP00000335493 | ENSP00000309161 | Forkhead box protein D2; Probable transcription factor involved in embryogenesis and somatogenesis; Forkhead boxes | Zinc finger protein 471; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.482 |
FOXI2 | SLC6A15 | ENSP00000373572 | ENSP00000266682 | Forkhead box protein I2; Possible transcriptional activator; Forkhead boxes | Sodium-dependent neutral amino acid transporter B(0)AT2; Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1-1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent; Solute carriers | 0.422 |
FOXI2 | SOX21 | ENSP00000373572 | ENSP00000366144 | Forkhead box protein I2; Possible transcriptional activator; Forkhead boxes | Transcription factor SOX-21; May play a role as an activator of transcription of OPRM1; SRY-boxes | 0.405 |
FOXI2 | ZNF471 | ENSP00000373572 | ENSP00000309161 | Forkhead box protein I2; Possible transcriptional activator; Forkhead boxes | Zinc finger protein 471; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.560 |
KIAA1755 | ZNF471 | ENSP00000279024 | ENSP00000309161 | Uncharacterized protein KIAA1755; KIAA1755 | Zinc finger protein 471; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.559 |
SLC6A15 | FOXI2 | ENSP00000266682 | ENSP00000373572 | Sodium-dependent neutral amino acid transporter B(0)AT2; Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1-1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent; Solute carriers | Forkhead box protein I2; Possible transcriptional activator; Forkhead boxes | 0.422 |
SLC6A15 | ZNF471 | ENSP00000266682 | ENSP00000309161 | Sodium-dependent neutral amino acid transporter B(0)AT2; Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1-1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent; Solute carriers | Zinc finger protein 471; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.434 |
SOX21 | FOXI2 | ENSP00000366144 | ENSP00000373572 | Transcription factor SOX-21; May play a role as an activator of transcription of OPRM1; SRY-boxes | Forkhead box protein I2; Possible transcriptional activator; Forkhead boxes | 0.405 |
SOX21 | ZNF471 | ENSP00000366144 | ENSP00000309161 | Transcription factor SOX-21; May play a role as an activator of transcription of OPRM1; SRY-boxes | Zinc finger protein 471; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.479 |
SUSD5 | FOXB1 | ENSP00000308727 | ENSP00000379369 | Sushi domain containing 5 | Forkhead box B1 | 0.420 |
SUSD5 | FOXD2 | ENSP00000308727 | ENSP00000335493 | Sushi domain containing 5 | Forkhead box protein D2; Probable transcription factor involved in embryogenesis and somatogenesis; Forkhead boxes | 0.440 |
SUSD5 | ZNF471 | ENSP00000308727 | ENSP00000309161 | Sushi domain containing 5 | Zinc finger protein 471; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.539 |
TRIM28 | ZNF471 | ENSP00000253024 | ENSP00000309161 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 471; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.904 |
ZNF471 | AMZ1 | ENSP00000309161 | ENSP00000308149 | Zinc finger protein 471; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Archaemetzincin-1; Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2; Belongs to the peptidase M54 family | 0.429 |
ZNF471 | BAZ1A | ENSP00000309161 | ENSP00000353458 | Zinc finger protein 471; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Bromodomain adjacent to zinc finger domain protein 1A; Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S pha [...] | 0.568 |