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  • 11.0 [archived version]
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SOX21 SOX21 SLC6A15 SLC6A15 FOXI2 FOXI2 FOXB1 FOXB1 BAZ1A BAZ1A ZNF471 ZNF471 SUSD5 SUSD5 TRIM28 TRIM28 FOXD2 FOXD2 KIAA1755 KIAA1755 AMZ1 AMZ1
"ZNF471" - Zinc finger protein 471 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF471Zinc finger protein 471; May be involved in transcriptional regulation; Zinc fingers C2H2-type (626 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
  0.904
BAZ1A
Bromodomain adjacent to zinc finger domain protein 1A; Component of the ACF complex, an ATP-dependent chromatin remodeling complex, that regulates spacing of nucleosomes using ATP to generate evenly spaced nucleosomes along the chromatin. The ATPase activity of the complex is regulated by the length of flanking DNA. Also involved in facilitating the DNA replication process. BAZ1A is the accessory, non-catalytic subunit of the complex which can enhance and direct the process provided by the ATPase subunit, SMARCA5, probably through targeting pericentromeric heterochromatin in late S pha [...] (1556 aa)
       
 
  0.568
FOXI2
Forkhead box protein I2; Possible transcriptional activator; Forkhead boxes (318 aa)
       
 
  0.560
KIAA1755
Uncharacterized protein KIAA1755; KIAA1755 (1200 aa)
           
  0.559
SUSD5
Sushi domain containing 5 (629 aa)
           
  0.539
FOXD2
Forkhead box protein D2; Probable transcription factor involved in embryogenesis and somatogenesis; Forkhead boxes (495 aa)
       
 
  0.482
SOX21
Transcription factor SOX-21; May play a role as an activator of transcription of OPRM1; SRY-boxes (276 aa)
       
 
  0.479
FOXB1
Forkhead box B1 (325 aa)
       
 
  0.468
SLC6A15
Sodium-dependent neutral amino acid transporter B(0)AT2; Functions as a sodium-dependent neutral amino acid transporter. Exhibits preference for the branched-chain amino acids, particularly leucine, valine and isoleucine and methionine. Mediates the saturable, pH-sensitive and electrogenic cotransport of proline and sodium ions with a stoichiometry of 1-1. May have a role as transporter for neurotransmitter precursors into neurons. In contrast to other members of the neurotransmitter transporter family, does not appear to be chloride-dependent; Solute carriers (730 aa)
     
   
  0.434
AMZ1
Archaemetzincin-1; Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2; Belongs to the peptidase M54 family (498 aa)
           
  0.429
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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