THAP6 protein (human) - STRING database

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

THAP6

THAP domain containing 6 (222 aa)

Predicted Functional Partners:

FBXO47

0.697

FAM26D

0.676

THAP8

0.669

N6AMT2

0.667

PTRH1

0.573

RPL7L1

0.571

THAP10

0.559

TMED5

0.544

UGT3A2

0.523

UGT3A1

0.523

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAM26D	FBXO47	ENSP00000385836	ENSP00000367319	Calcium homeostasis modulator protein 4; Pore-forming subunit of a voltage-gated ion channel	F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation; F-boxes other	0.838
FAM26D	THAP6	ENSP00000385836	ENSP00000309007	Calcium homeostasis modulator protein 4; Pore-forming subunit of a voltage-gated ion channel	THAP domain containing 6	0.676
FAM26D	UGT3A1	ENSP00000385836	ENSP00000274278	Calcium homeostasis modulator protein 4; Pore-forming subunit of a voltage-gated ion channel	UDP-glucuronosyltransferase 3A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family	0.697
FAM26D	UGT3A2	ENSP00000385836	ENSP00000282507	Calcium homeostasis modulator protein 4; Pore-forming subunit of a voltage-gated ion channel	UDP-glucuronosyltransferase 3A2; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family	0.697
FBXO47	FAM26D	ENSP00000367319	ENSP00000385836	F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation; F-boxes other	Calcium homeostasis modulator protein 4; Pore-forming subunit of a voltage-gated ion channel	0.838
FBXO47	THAP6	ENSP00000367319	ENSP00000309007	F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation; F-boxes other	THAP domain containing 6	0.697
FBXO47	UGT3A1	ENSP00000367319	ENSP00000274278	F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation; F-boxes other	UDP-glucuronosyltransferase 3A1; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family	0.678
FBXO47	UGT3A2	ENSP00000367319	ENSP00000282507	F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation; F-boxes other	UDP-glucuronosyltransferase 3A2; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family	0.678
N6AMT2	PTRH1	ENSP00000372206	ENSP00000418661	EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-79’	peptidyl-tRNA hydrolase 1 homolog; Belongs to the PTH family	0.555
N6AMT2	RPL7L1	ENSP00000372206	ENSP00000418221	EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-79’	Ribosomal protein L7 like 1	0.564
N6AMT2	THAP6	ENSP00000372206	ENSP00000309007	EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-79’	THAP domain containing 6	0.667
N6AMT2	TMED5	ENSP00000372206	ENSP00000359305	EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-79’	Transmembrane emp24 domain-containing protein 5; Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle- mediated retrograde transport; Transmembrane p24 trafficking proteins	0.529
PTRH1	N6AMT2	ENSP00000418661	ENSP00000372206	peptidyl-tRNA hydrolase 1 homolog; Belongs to the PTH family	EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-79’	0.555
PTRH1	RPL7L1	ENSP00000418661	ENSP00000418221	peptidyl-tRNA hydrolase 1 homolog; Belongs to the PTH family	Ribosomal protein L7 like 1	0.475
PTRH1	THAP6	ENSP00000418661	ENSP00000309007	peptidyl-tRNA hydrolase 1 homolog; Belongs to the PTH family	THAP domain containing 6	0.573
PTRH1	TMED5	ENSP00000418661	ENSP00000359305	peptidyl-tRNA hydrolase 1 homolog; Belongs to the PTH family	Transmembrane emp24 domain-containing protein 5; Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle- mediated retrograde transport; Transmembrane p24 trafficking proteins	0.410
RPL7L1	N6AMT2	ENSP00000418221	ENSP00000372206	Ribosomal protein L7 like 1	EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at ’Lys-79’	0.564
RPL7L1	PTRH1	ENSP00000418221	ENSP00000418661	Ribosomal protein L7 like 1	peptidyl-tRNA hydrolase 1 homolog; Belongs to the PTH family	0.475
RPL7L1	THAP6	ENSP00000418221	ENSP00000309007	Ribosomal protein L7 like 1	THAP domain containing 6	0.571
RPL7L1	TMED5	ENSP00000418221	ENSP00000359305	Ribosomal protein L7 like 1	Transmembrane emp24 domain-containing protein 5; Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle- mediated retrograde transport; Transmembrane p24 trafficking proteins	0.438

page 1 of 3

Network

Cooccurrence

Textmining

Coexpression

Experiments

Neighborhood

Databases

Fusion

© STRING Consortium 2020

Credits

Access

Info

About