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STRINGSTRING
UMODL1 UMODL1 LIPI LIPI C2CD2 C2CD2 RIPK4 RIPK4 SCAMP4 SCAMP4 ZBTB21 ZBTB21 ZZZ3 ZZZ3 ZNF217 ZNF217 ZNF22 ZNF22 ZNF532 ZNF532 ZNF608 ZNF608
"ZBTB21" - Zinc finger and BTB domain-containing protein 21 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZBTB21Zinc finger and BTB domain-containing protein 21; Acts as a transcription repressor; BTB domain containing (1066 aa)    
Predicted Functional Partners:
ZNF532
Zinc finger protein 532; May be involved in transcriptional regulation; Zinc fingers C2H2-type (1301 aa)
            
  0.719
LIPI
Lipase member I; Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG); Belongs to the AB hydrolase superfamily. Lipase family (481 aa)
            
  0.671
ZNF608
Zinc finger protein 608; Transcription factor, which represses ZNF609 transcription; Zinc fingers C2H2-type (1512 aa)
            
  0.638
ZNF22
Zinc finger protein 22; Binds DNA through the consensus sequence 5’-CAATG-3’. May be involved in transcriptional regulation and may play a role in tooth formation (By similarity); Zinc fingers C2H2-type (224 aa)
            
  0.587
ZZZ3
ZZ-type zinc finger-containing protein 3; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (903 aa)
            
  0.582
C2CD2
C2 calcium dependent domain containing 2 (696 aa)
            
  0.582
UMODL1
Uromodulin like 1 (1446 aa)
            
  0.572
ZNF217
Zinc finger protein 217; Binds to the promoters of target genes and functions as repressor. Promotes cell proliferation and antagonizes cell death. Promotes phosphorylation of AKT1 at ’Ser-473’; Zinc fingers C2H2-type (1048 aa)
            
  0.554
RIPK4
Receptor-interacting serine/threonine-protein kinase 4; Involved in stratified epithelial development. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family (784 aa)
      
 
  0.550
SCAMP4
Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking; Secretory carrier membrane proteins (229 aa)
            
  0.540
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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