| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENO2 | GPR151 | ENSP00000437402 | ENSP00000308733 | Gamma-enolase; Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity); Enolases | Probable G-protein coupled receptor 151; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.574 |
| GAL | GNG8 | ENSP00000265643 | ENSP00000300873 | Galanin peptides; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction | 0.900 |
| GAL | GPR151 | ENSP00000265643 | ENSP00000308733 | Galanin peptides; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family | Probable G-protein coupled receptor 151; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.663 |
| GNG8 | GAL | ENSP00000300873 | ENSP00000265643 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction | Galanin peptides; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family | 0.900 |
| GNG8 | GPR151 | ENSP00000300873 | ENSP00000308733 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction | Probable G-protein coupled receptor 151; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.540 |
| GPR133 | GPR151 | ENSP00000261654 | ENSP00000308733 | Adhesion G-protein coupled receptor D1; Orphan receptor. Signals via G(s)-alpha family of G- proteins. Has protumorigenic function especially in glioblastoma | Probable G-protein coupled receptor 151; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.618 |
| GPR151 | ENO2 | ENSP00000308733 | ENSP00000437402 | Probable G-protein coupled receptor 151; Orphan receptor; G protein-coupled receptors, Class A orphans | Gamma-enolase; Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity); Enolases | 0.574 |
| GPR151 | GAL | ENSP00000308733 | ENSP00000265643 | Probable G-protein coupled receptor 151; Orphan receptor; G protein-coupled receptors, Class A orphans | Galanin peptides; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family | 0.663 |
| GPR151 | GNG8 | ENSP00000308733 | ENSP00000300873 | Probable G-protein coupled receptor 151; Orphan receptor; G protein-coupled receptors, Class A orphans | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction | 0.540 |
| GPR151 | GPR133 | ENSP00000308733 | ENSP00000261654 | Probable G-protein coupled receptor 151; Orphan receptor; G protein-coupled receptors, Class A orphans | Adhesion G-protein coupled receptor D1; Orphan receptor. Signals via G(s)-alpha family of G- proteins. Has protumorigenic function especially in glioblastoma | 0.618 |
| GPR151 | KCTD16 | ENSP00000308733 | ENSP00000426548 | Probable G-protein coupled receptor 151; Orphan receptor; G protein-coupled receptors, Class A orphans | BTB/POZ domain-containing protein KCTD16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity) | 0.539 |
| GPR151 | ODF3 | ENSP00000308733 | ENSP00000325868 | Probable G-protein coupled receptor 151; Orphan receptor; G protein-coupled receptors, Class A orphans | Outer dense fiber protein 3; Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail | 0.571 |
| GPR151 | RBM27 | ENSP00000308733 | ENSP00000265271 | Probable G-protein coupled receptor 151; Orphan receptor; G protein-coupled receptors, Class A orphans | RNA-binding protein 27; RNA binding motif containing | 0.537 |
| GPR151 | RPS7 | ENSP00000308733 | ENSP00000339095 | Probable G-protein coupled receptor 151; Orphan receptor; G protein-coupled receptors, Class A orphans | 40S ribosomal protein S7; Required for rRNA maturation; Belongs to the eukaryotic ribosomal protein eS7 family | 0.559 |
| GPR151 | SH3RF2 | ENSP00000308733 | ENSP00000424497 | Probable G-protein coupled receptor 151; Orphan receptor; G protein-coupled receptors, Class A orphans | Putative E3 ubiquitin-protein ligase SH3RF2; Inhibits PPP1CA phosphatase activity. May be a E3 ubiquitin-protein ligase (Potential). May play a role in cardiac function; Belongs to the SH3RF family | 0.545 |
| GPR151 | TCERG1 | ENSP00000308733 | ENSP00000296702 | Probable G-protein coupled receptor 151; Orphan receptor; G protein-coupled receptors, Class A orphans | Transcription elongation regulator 1; Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter | 0.690 |
| KCTD16 | GPR151 | ENSP00000426548 | ENSP00000308733 | BTB/POZ domain-containing protein KCTD16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity) | Probable G-protein coupled receptor 151; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.539 |
| KCTD16 | SH3RF2 | ENSP00000426548 | ENSP00000424497 | BTB/POZ domain-containing protein KCTD16; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity) | Putative E3 ubiquitin-protein ligase SH3RF2; Inhibits PPP1CA phosphatase activity. May be a E3 ubiquitin-protein ligase (Potential). May play a role in cardiac function; Belongs to the SH3RF family | 0.449 |
| ODF3 | GPR151 | ENSP00000325868 | ENSP00000308733 | Outer dense fiber protein 3; Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail | Probable G-protein coupled receptor 151; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.571 |
| ODF3 | RPS7 | ENSP00000325868 | ENSP00000339095 | Outer dense fiber protein 3; Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail. May help to maintain the passive elastic structures and elastic recoil of the sperm tail | 40S ribosomal protein S7; Required for rRNA maturation; Belongs to the eukaryotic ribosomal protein eS7 family | 0.554 |
