node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIP | DCAKD | ENSP00000279146 | ENSP00000308515 | AH receptor-interacting protein; May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting; FKBP prolyl isomerases | dephospho-CoA kinase domain containing | 0.547 |
AIP | PLBD2 | ENSP00000279146 | ENSP00000280800 | AH receptor-interacting protein; May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting; FKBP prolyl isomerases | Putative phospholipase B-like 2; Putative phospholipase | 0.509 |
DCAKD | AIP | ENSP00000308515 | ENSP00000279146 | dephospho-CoA kinase domain containing | AH receptor-interacting protein; May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting; FKBP prolyl isomerases | 0.547 |
DCAKD | FRMD4A | ENSP00000308515 | ENSP00000350032 | dephospho-CoA kinase domain containing | FERM domain-containing protein 4A; Scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex (By similarity). Plays a redundant role with FRMD4B in epithelial polarization (By similarity). May regulate MAPT secretion by activating ARF6-signaling; FERM domain containing | 0.662 |
DCAKD | GART | ENSP00000308515 | ENSP00000371253 | dephospho-CoA kinase domain containing | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family | 0.636 |
DCAKD | LRRC37A | ENSP00000308515 | ENSP00000326324 | dephospho-CoA kinase domain containing | Leucine-rich repeat-containing protein 37A; Leucine rich repeat containing 37A | 0.558 |
DCAKD | LRRC37A2 | ENSP00000308515 | ENSP00000459551 | dephospho-CoA kinase domain containing | Leucine-rich repeat-containing protein 37A2; Leucine rich repeat containing 37 member A2 | 0.668 |
DCAKD | PANK4 | ENSP00000308515 | ENSP00000367727 | dephospho-CoA kinase domain containing | Pantothenate kinase 4; Plays a role in the physiological regulation of the intracellular CoA concentration | 0.642 |
DCAKD | PARD3B | ENSP00000308515 | ENSP00000351618 | dephospho-CoA kinase domain containing | Partitioning defective 3 homolog B; Putative adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions; Belongs to the PAR3 family | 0.654 |
DCAKD | PLBD2 | ENSP00000308515 | ENSP00000280800 | dephospho-CoA kinase domain containing | Putative phospholipase B-like 2; Putative phospholipase | 0.628 |
DCAKD | PPCDC | ENSP00000308515 | ENSP00000343190 | dephospho-CoA kinase domain containing | Phosphopantothenoylcysteine decarboxylase; Necessary for the biosynthesis of coenzyme A. Catalyzes the decarboxylation of 4-phosphopantothenoylcysteine to form 4’- phosphopantotheine | 0.715 |
DCAKD | PPCS | ENSP00000308515 | ENSP00000361642 | dephospho-CoA kinase domain containing | Phosphopantothenate--cysteine ligase; Catalyzes the first step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4’- phosphopantothenate to form 4-phosphopantothenoylcysteine; Belongs to the PPC synthetase family | 0.698 |
FRMD4A | DCAKD | ENSP00000350032 | ENSP00000308515 | FERM domain-containing protein 4A; Scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex (By similarity). Plays a redundant role with FRMD4B in epithelial polarization (By similarity). May regulate MAPT secretion by activating ARF6-signaling; FERM domain containing | dephospho-CoA kinase domain containing | 0.662 |
FRMD4A | PARD3B | ENSP00000350032 | ENSP00000351618 | FERM domain-containing protein 4A; Scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex (By similarity). Plays a redundant role with FRMD4B in epithelial polarization (By similarity). May regulate MAPT secretion by activating ARF6-signaling; FERM domain containing | Partitioning defective 3 homolog B; Putative adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions; Belongs to the PAR3 family | 0.752 |
GART | DCAKD | ENSP00000371253 | ENSP00000308515 | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family | dephospho-CoA kinase domain containing | 0.636 |
GART | PPCS | ENSP00000371253 | ENSP00000361642 | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family | Phosphopantothenate--cysteine ligase; Catalyzes the first step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4’- phosphopantothenate to form 4-phosphopantothenoylcysteine; Belongs to the PPC synthetase family | 0.488 |
LRRC37A | DCAKD | ENSP00000326324 | ENSP00000308515 | Leucine-rich repeat-containing protein 37A; Leucine rich repeat containing 37A | dephospho-CoA kinase domain containing | 0.558 |
LRRC37A2 | DCAKD | ENSP00000459551 | ENSP00000308515 | Leucine-rich repeat-containing protein 37A2; Leucine rich repeat containing 37 member A2 | dephospho-CoA kinase domain containing | 0.668 |
PANK4 | DCAKD | ENSP00000367727 | ENSP00000308515 | Pantothenate kinase 4; Plays a role in the physiological regulation of the intracellular CoA concentration | dephospho-CoA kinase domain containing | 0.642 |
PANK4 | PPCDC | ENSP00000367727 | ENSP00000343190 | Pantothenate kinase 4; Plays a role in the physiological regulation of the intracellular CoA concentration | Phosphopantothenoylcysteine decarboxylase; Necessary for the biosynthesis of coenzyme A. Catalyzes the decarboxylation of 4-phosphopantothenoylcysteine to form 4’- phosphopantotheine | 0.970 |