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STRINGSTRING
BRK1 BRK1 NHSL1 NHSL1 WASF1 WASF1 ABI2 ABI2 CYFIP1 CYFIP1 HEATR9 HEATR9 AMZ1 AMZ1 OR6T1 OR6T1 SEL1L3 SEL1L3 CCDC71 CCDC71 CDADC1 CDADC1
"AMZ1" - Archaemetzincin-1 in Homo sapiens
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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textmining
co-expression
protein homology
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AMZ1Archaemetzincin-1; Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2; Belongs to the peptidase M54 family (498 aa)    
Predicted Functional Partners:
NHSL1
NHS-like protein 1; NHS like 1; Belongs to the NHS family (1610 aa)
        
      0.827
ABI2
Abl interactor 2; May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity) (513 aa)
        
      0.683
CYFIP1
Cytoplasmic FMR1-interacting protein 1; Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the [...] (1253 aa)
        
      0.666
WASF1
Wiskott-Aldrich syndrome protein family member 1; Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity). As component of the WAVE1 complex, required for BDNF- NTRK2 endocytic trafficking and signaling from early endosomes (By similarity); A-kinase anchoring proteins (559 aa)
        
      0.666
OR6T1
Olfactory receptor 6T1; Odorant receptor; Olfactory receptors, family 6 (323 aa)
            
  0.641
CCDC71
Coiled-coil domain containing 71 (467 aa)
            
  0.601
CDADC1
Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis; Belongs to the cytidine and deoxycytidylate deaminase family (514 aa)
            
  0.572
BRK1
Protein BRICK1; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF- NTRK2 endocytic trafficking and signaling from early endosomes (By similarity) (75 aa)
        
      0.571
SEL1L3
Protein sel-1 homolog 3; SEL1L family member 3 (1132 aa)
            
  0.569
HEATR9
Protein HEATR9; Armadillo-like helical domain containing (570 aa)
            
  0.560
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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