• Version:
  • 11.0 [archived version]
STRINGSTRING
GRAMD3 GRAMD3 DNAJC27 DNAJC27 MTIF3 MTIF3 QPCTL QPCTL JADE3 JADE3 TMEM160 TMEM160 POC5 POC5 ZNF608 ZNF608 ZBTB40 ZBTB40 ZNF532 ZNF532 ATN1 ATN1
"ZNF608" - Zinc finger protein 608 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF608Zinc finger protein 608; Transcription factor, which represses ZNF609 transcription; Zinc fingers C2H2-type (1512 aa)    
Predicted Functional Partners:
TMEM160
Transmembrane protein 160 (188 aa)
           
  0.700
ZBTB40
Zinc finger and BTB domain-containing protein 40; May be involved in transcriptional regulation; BTB domain containing (1239 aa)
           
  0.691
ATN1
Atrophin-1; Transcriptional corepressor. Recruits NR2E1 to repress transcription. Promotes vascular smooth cell (VSMC) migration and orientation (By similarity). Corepressor of MTG8 transcriptional repression. Has some intrinsic repression activity which is independent of the number of poly-Asn (polyQ) repeats (1190 aa)
     
 
  0.687
MTIF3
Translation initiation factor IF-3, mitochondrial; IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins (278 aa)
           
  0.669
DNAJC27
DnaJ homolog subfamily C member 27; GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling; DNAJ heat shock proteins (273 aa)
           
  0.669
JADE3
Protein Jade-3; Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo; PHD finger proteins (823 aa)
           
  0.659
QPCTL
Glutaminyl-peptide cyclotransferase-like protein; Responsible for the biosynthesis of pyroglutamyl peptides (382 aa)
           
  0.658
ZNF532
Zinc finger protein 532; May be involved in transcriptional regulation; Zinc fingers C2H2-type (1301 aa)
     
   
  0.650
POC5
Centrosomal protein POC5; Essential for the assembly of the distal half of centrioles, required for centriole elongation; Belongs to the POC5 family (575 aa)
           
  0.647
GRAMD3
GRAM domain-containing protein 2B; GRAM domain containing 3 (447 aa)
           
  0.642
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (1%) [HD]