• Version:
  • 11.0 [archived version]
STRINGSTRING
TTC39C TTC39C TTC4 TTC4 TTC9C TTC9C TTC26 TTC26 TTC5 TTC5 TTC36 TTC36 HAAO HAAO F13B F13B FTCD FTCD HGD HGD AGXT AGXT
"TTC36" - Tetratricopeptide repeat domain containing in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
Score
TTC36Tetratricopeptide repeat domain containing (189 aa)    
Predicted Functional Partners:
TTC26
Intraflagellar transport protein 56; Component of the intraflagellar transport (IFT) complex B required for transport of proteins in the motile cilium. Required for transport of specific ciliary cargo proteins related to motility, while it is neither required for IFT complex B assembly or motion nor for cilium assembly. Required for efficient coupling between the accumulation of GLI3 at the ciliary tip and its dissociation from SUFU; Belongs to the IFT56 family (554 aa)
           
  0.797
TTC9C
Tetratricopeptide repeat domain containing; Belongs to the TTC9 family (171 aa)
           
  0.765
TTC4
Tetratricopeptide repeat domain containing; Belongs to the TTC4 family (387 aa)
           
  0.730
HGD
Homogentisate 1,2-dioxygenase (445 aa)
     
   
  0.686
FTCD
Formimidoyltransferase-cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool; In the N-terminal section; belongs to the formiminotransferase family (541 aa)
     
        0.660
HAAO
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family (286 aa)
     
        0.649
AGXT
Alanine-glyoxylate aminotransferase (392 aa)
     
        0.641
TTC39C
Tetratricopeptide repeat domain containing (583 aa)
     
   
  0.634
TTC5
Tetratricopeptide repeat protein 5; Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity); Tetratricopeptide repeat domain containing (440 aa)
           
  0.630
F13B
Coagulation factor XIII B chain; The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin; Sushi domain containing (661 aa)
     
        0.630
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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