node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTRT2 | NKG7 | ENSP00000367658 | ENSP00000221978 | Actin related protein T2 | Protein NKG7; Natural killer cell granule protein 7; Belongs to the PMP-22/EMP/MP20 family | 0.406 |
ACTRT2 | OR4D10 | ENSP00000367658 | ENSP00000436424 | Actin related protein T2 | Olfactory receptor 4D10; Odorant receptor; Olfactory receptors, family 4 | 0.530 |
ACTRT2 | SAAL1 | ENSP00000367658 | ENSP00000432487 | Actin related protein T2 | Protein SAAL1; Plays a role in promoting the proliferation of synovial fibroblasts in response to proinflammatory stimuli; Armadillo-like helical domain containing | 0.603 |
ACTRT2 | ZBTB5 | ENSP00000367658 | ENSP00000307604 | Actin related protein T2 | Zinc finger and BTB domain-containing protein 5; May be involved in transcriptional regulation; BTB domain containing | 0.602 |
CCDC39 | CSDC2 | ENSP00000405708 | ENSP00000302485 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly | Cold shock domain-containing protein C2; RNA-binding factor which binds specifically to the very 3’-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity) | 0.451 |
CCDC39 | MESDC1 | ENSP00000405708 | ENSP00000267984 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly | Talin rod domain-containing protein 1; Actin-binding protein which may have an oncogenic function and regulates cell proliferation, migration and invasion in cancer cells | 0.545 |
CCDC39 | TMCC1 | ENSP00000405708 | ENSP00000376930 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly | Transmembrane and coiled-coil domain containing | 0.536 |
CCDC39 | TMEM181 | ENSP00000405708 | ENSP00000356057 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly | Transmembrane protein 181; Mediates action of cytolethal distending toxins (CDT), which are secreted by many pathogenic bacteria. Expression level of TMEM181 is rate-limiting for intoxication | 0.497 |
CCDC39 | ZBTB5 | ENSP00000405708 | ENSP00000307604 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly | Zinc finger and BTB domain-containing protein 5; May be involved in transcriptional regulation; BTB domain containing | 0.528 |
CSDC2 | CCDC39 | ENSP00000302485 | ENSP00000405708 | Cold shock domain-containing protein C2; RNA-binding factor which binds specifically to the very 3’-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity) | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly | 0.451 |
CSDC2 | MESDC1 | ENSP00000302485 | ENSP00000267984 | Cold shock domain-containing protein C2; RNA-binding factor which binds specifically to the very 3’-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity) | Talin rod domain-containing protein 1; Actin-binding protein which may have an oncogenic function and regulates cell proliferation, migration and invasion in cancer cells | 0.514 |
CSDC2 | TMCC1 | ENSP00000302485 | ENSP00000376930 | Cold shock domain-containing protein C2; RNA-binding factor which binds specifically to the very 3’-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity) | Transmembrane and coiled-coil domain containing | 0.515 |
CSDC2 | TMEM181 | ENSP00000302485 | ENSP00000356057 | Cold shock domain-containing protein C2; RNA-binding factor which binds specifically to the very 3’-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity) | Transmembrane protein 181; Mediates action of cytolethal distending toxins (CDT), which are secreted by many pathogenic bacteria. Expression level of TMEM181 is rate-limiting for intoxication | 0.442 |
CSDC2 | ZBTB5 | ENSP00000302485 | ENSP00000307604 | Cold shock domain-containing protein C2; RNA-binding factor which binds specifically to the very 3’-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity) | Zinc finger and BTB domain-containing protein 5; May be involved in transcriptional regulation; BTB domain containing | 0.508 |
MESDC1 | CCDC39 | ENSP00000267984 | ENSP00000405708 | Talin rod domain-containing protein 1; Actin-binding protein which may have an oncogenic function and regulates cell proliferation, migration and invasion in cancer cells | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly | 0.545 |
MESDC1 | CSDC2 | ENSP00000267984 | ENSP00000302485 | Talin rod domain-containing protein 1; Actin-binding protein which may have an oncogenic function and regulates cell proliferation, migration and invasion in cancer cells | Cold shock domain-containing protein C2; RNA-binding factor which binds specifically to the very 3’-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity) | 0.514 |
MESDC1 | TMCC1 | ENSP00000267984 | ENSP00000376930 | Talin rod domain-containing protein 1; Actin-binding protein which may have an oncogenic function and regulates cell proliferation, migration and invasion in cancer cells | Transmembrane and coiled-coil domain containing | 0.585 |
MESDC1 | TMEM181 | ENSP00000267984 | ENSP00000356057 | Talin rod domain-containing protein 1; Actin-binding protein which may have an oncogenic function and regulates cell proliferation, migration and invasion in cancer cells | Transmembrane protein 181; Mediates action of cytolethal distending toxins (CDT), which are secreted by many pathogenic bacteria. Expression level of TMEM181 is rate-limiting for intoxication | 0.553 |
MESDC1 | ZBTB5 | ENSP00000267984 | ENSP00000307604 | Talin rod domain-containing protein 1; Actin-binding protein which may have an oncogenic function and regulates cell proliferation, migration and invasion in cancer cells | Zinc finger and BTB domain-containing protein 5; May be involved in transcriptional regulation; BTB domain containing | 0.555 |
MRPS31 | ZBTB5 | ENSP00000315397 | ENSP00000307604 | Mitochondrial ribosomal protein S31 | Zinc finger and BTB domain-containing protein 5; May be involved in transcriptional regulation; BTB domain containing | 0.517 |