node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MYH1 | MYH13 | ENSP00000226207 | ENSP00000404570 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Myosin-13; Fast twitching myosin mediating the high-velocity and low-tension contractions of specific striated muscles; Myosin heavy chains | 0.912 |
MYH1 | MYH3 | ENSP00000226207 | ENSP00000464317 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Myosin-3; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.733 |
MYH1 | MYH6 | ENSP00000226207 | ENSP00000386041 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Myosin-6; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.908 |
MYH1 | MYH8 | ENSP00000226207 | ENSP00000384330 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Myosin-8; Muscle contraction; Myosin heavy chains | 0.933 |
MYH1 | MYL1 | ENSP00000226207 | ENSP00000307280 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Myosin light chain 1/3, skeletal muscle isoform; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | 0.982 |
MYH1 | NEB | ENSP00000226207 | ENSP00000484342 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Nebulin | 0.618 |
MYH1 | TNNC2 | ENSP00000226207 | ENSP00000361636 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Troponin C, skeletal muscle; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components- Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments; EF-hand domain containing | 0.815 |
MYH1 | TNNI2 | ENSP00000226207 | ENSP00000371331 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Troponin I, fast skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity | 0.748 |
MYH1 | TNNT3 | ENSP00000226207 | ENSP00000278317 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity | 0.835 |
MYH1 | TTN | ENSP00000226207 | ENSP00000467141 | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | Titin; Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase; Fibronectin type III domain containing | 0.864 |
MYH13 | MYH1 | ENSP00000404570 | ENSP00000226207 | Myosin-13; Fast twitching myosin mediating the high-velocity and low-tension contractions of specific striated muscles; Myosin heavy chains | Myosin-1; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.912 |
MYH13 | MYH3 | ENSP00000404570 | ENSP00000464317 | Myosin-13; Fast twitching myosin mediating the high-velocity and low-tension contractions of specific striated muscles; Myosin heavy chains | Myosin-3; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.722 |
MYH13 | MYH6 | ENSP00000404570 | ENSP00000386041 | Myosin-13; Fast twitching myosin mediating the high-velocity and low-tension contractions of specific striated muscles; Myosin heavy chains | Myosin-6; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family | 0.904 |
MYH13 | MYH8 | ENSP00000404570 | ENSP00000384330 | Myosin-13; Fast twitching myosin mediating the high-velocity and low-tension contractions of specific striated muscles; Myosin heavy chains | Myosin-8; Muscle contraction; Myosin heavy chains | 0.958 |
MYH13 | MYL1 | ENSP00000404570 | ENSP00000307280 | Myosin-13; Fast twitching myosin mediating the high-velocity and low-tension contractions of specific striated muscles; Myosin heavy chains | Myosin light chain 1/3, skeletal muscle isoform; Regulatory light chain of myosin. Does not bind calcium; EF-hand domain containing | 0.981 |
MYH13 | NEB | ENSP00000404570 | ENSP00000484342 | Myosin-13; Fast twitching myosin mediating the high-velocity and low-tension contractions of specific striated muscles; Myosin heavy chains | Nebulin | 0.568 |
MYH13 | TNNC2 | ENSP00000404570 | ENSP00000361636 | Myosin-13; Fast twitching myosin mediating the high-velocity and low-tension contractions of specific striated muscles; Myosin heavy chains | Troponin C, skeletal muscle; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components- Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments; EF-hand domain containing | 0.447 |
MYH13 | TNNI2 | ENSP00000404570 | ENSP00000371331 | Myosin-13; Fast twitching myosin mediating the high-velocity and low-tension contractions of specific striated muscles; Myosin heavy chains | Troponin I, fast skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity | 0.462 |
MYH13 | TNNT3 | ENSP00000404570 | ENSP00000278317 | Myosin-13; Fast twitching myosin mediating the high-velocity and low-tension contractions of specific striated muscles; Myosin heavy chains | Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity | 0.462 |
MYH13 | TTN | ENSP00000404570 | ENSP00000467141 | Myosin-13; Fast twitching myosin mediating the high-velocity and low-tension contractions of specific striated muscles; Myosin heavy chains | Titin; Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase; Fibronectin type III domain containing | 0.841 |