• Version:
  • 11.0 [archived version]
STRINGSTRING
CDKL1 CDKL1 PCDHB1 PCDHB1 TMEM211 TMEM211 TMEM213 TMEM213 MSLNL MSLNL B4GALNT3 B4GALNT3 GRAMD1C GRAMD1C TTC9 TTC9 SEC14L3 SEC14L3 TMEM205 TMEM205
"PCDHB1" - Protocadherin beta-1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
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[Homology]
Score
PCDHB1Protocadherin beta-1; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins (818 aa)    
Predicted Functional Partners:
CDKL1
Cyclin-dependent kinase-like 1; Cyclin dependent kinase like 1 (358 aa)
     
   
  0.743
TMEM213
Transmembrane protein 213 (107 aa)
     
   
  0.488
TMEM211
Transmembrane protein 211 (129 aa)
       
 
  0.475
TTC9
Tetratricopeptide repeat domain containing; Belongs to the TTC9 family (222 aa)
     
   
  0.441
MSLNL
Mesothelin-like protein; May play a role in cellular adhesion (752 aa)
           
  0.434
GRAMD1C
GRAM domain containing 1C (662 aa)
           
  0.429
TMEM205
Transmembrane protein 205; In cancer cells, plays a role in resistance to the chemotherapeutic agent cisplatin (189 aa)
           
  0.424
SEC14L3
SEC14-like protein 3; Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids; SEC14 family (400 aa)
     
   
  0.406
B4GALNT3
Beta-1,4-N-acetylgalactosaminyltransferase 3; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N’-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. Mediates the N,N’- diacetyllactosediamine formation on gastric mucosa; Belongs to the chondroitin N- acetylgalactosaminyltransferase family (998 aa)
     
   
  0.402
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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