• Version:
  • 11.0 [archived version]
STRINGSTRING
AGR3 AGR3 PCYOX1 PCYOX1 FAM172A FAM172A POGLUT1 POGLUT1 FKBP7 FKBP7 PATE1 PATE1 TGFBR1 TGFBR1 PATE4 PATE4 PATE3 PATE3 PATE2 PATE2 PLA2G1B PLA2G1B
"PATE1" - Prostate and testis expressed 1 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PATE1Prostate and testis expressed 1; Belongs to the PATE family (126 aa)    
Predicted Functional Partners:
PATE3
Prostate and testis expressed 3; Belongs to the PATE family (98 aa)
     
   
  0.711
PATE2
Prostate and testis expressed 2; LY6/PLAUR domain containing (113 aa)
           
  0.700
PLA2G1B
Phospholipase A2; PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides, this releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules; Belongs to the phospholipase A2 family (148 aa)
           
  0.643
TGFBR1
TGF-beta receptor type-1; Transmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogen [...] (503 aa)
           
  0.641
PATE4
Prostate and testis expressed protein 4; May modulate the function of nicotinic acetylcholine receptors. May enhance sperm motility; LY6/PLAUR domain containing (98 aa)
           
  0.591
FAM172A
Protein FAM172A; Family with sequence similarity 172 member A; Belongs to the UPF0528 family (416 aa)
           
  0.580
PCYOX1
Prenylcysteine oxidase 1; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (505 aa)
           
  0.571
FKBP7
Peptidylprolyl isomerase; EF-hand domain containing (222 aa)
           
  0.567
POGLUT1
Protein O-glucosyltransferase 1; Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C. Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2. Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development. Notch glucosylation does not affect Notch ligand binding. Required during early development to promote gastrulation- acts by mediating O- g [...] (392 aa)
           
  0.553
AGR3
Anterior gradient protein 3; Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells; Belongs to the AGR family (166 aa)
           
  0.552
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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