node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGR3 | FAM172A | ENSP00000308606 | ENSP00000379294 | Anterior gradient protein 3; Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells; Belongs to the AGR family | Protein FAM172A; Family with sequence similarity 172 member A; Belongs to the UPF0528 family | 0.604 |
AGR3 | FKBP7 | ENSP00000308606 | ENSP00000413152 | Anterior gradient protein 3; Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells; Belongs to the AGR family | Peptidylprolyl isomerase; EF-hand domain containing | 0.597 |
AGR3 | PATE1 | ENSP00000308606 | ENSP00000307164 | Anterior gradient protein 3; Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells; Belongs to the AGR family | Prostate and testis expressed 1; Belongs to the PATE family | 0.552 |
AGR3 | PCYOX1 | ENSP00000308606 | ENSP00000387654 | Anterior gradient protein 3; Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells; Belongs to the AGR family | Prenylcysteine oxidase 1; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine | 0.630 |
AGR3 | POGLUT1 | ENSP00000308606 | ENSP00000295588 | Anterior gradient protein 3; Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells; Belongs to the AGR family | Protein O-glucosyltransferase 1; Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C. Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2. Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development. Notch glucosylation does not affect Notch ligand binding. Required during early development to promote gastrulation- acts by mediating O- g [...] | 0.609 |
FAM172A | AGR3 | ENSP00000379294 | ENSP00000308606 | Protein FAM172A; Family with sequence similarity 172 member A; Belongs to the UPF0528 family | Anterior gradient protein 3; Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells; Belongs to the AGR family | 0.604 |
FAM172A | FKBP7 | ENSP00000379294 | ENSP00000413152 | Protein FAM172A; Family with sequence similarity 172 member A; Belongs to the UPF0528 family | Peptidylprolyl isomerase; EF-hand domain containing | 0.593 |
FAM172A | PATE1 | ENSP00000379294 | ENSP00000307164 | Protein FAM172A; Family with sequence similarity 172 member A; Belongs to the UPF0528 family | Prostate and testis expressed 1; Belongs to the PATE family | 0.580 |
FAM172A | PCYOX1 | ENSP00000379294 | ENSP00000387654 | Protein FAM172A; Family with sequence similarity 172 member A; Belongs to the UPF0528 family | Prenylcysteine oxidase 1; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine | 0.628 |
FAM172A | POGLUT1 | ENSP00000379294 | ENSP00000295588 | Protein FAM172A; Family with sequence similarity 172 member A; Belongs to the UPF0528 family | Protein O-glucosyltransferase 1; Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C. Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2. Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development. Notch glucosylation does not affect Notch ligand binding. Required during early development to promote gastrulation- acts by mediating O- g [...] | 0.604 |
FKBP7 | AGR3 | ENSP00000413152 | ENSP00000308606 | Peptidylprolyl isomerase; EF-hand domain containing | Anterior gradient protein 3; Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells; Belongs to the AGR family | 0.597 |
FKBP7 | FAM172A | ENSP00000413152 | ENSP00000379294 | Peptidylprolyl isomerase; EF-hand domain containing | Protein FAM172A; Family with sequence similarity 172 member A; Belongs to the UPF0528 family | 0.593 |
FKBP7 | PATE1 | ENSP00000413152 | ENSP00000307164 | Peptidylprolyl isomerase; EF-hand domain containing | Prostate and testis expressed 1; Belongs to the PATE family | 0.567 |
FKBP7 | PCYOX1 | ENSP00000413152 | ENSP00000387654 | Peptidylprolyl isomerase; EF-hand domain containing | Prenylcysteine oxidase 1; Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine | 0.671 |
FKBP7 | POGLUT1 | ENSP00000413152 | ENSP00000295588 | Peptidylprolyl isomerase; EF-hand domain containing | Protein O-glucosyltransferase 1; Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C. Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2. Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development. Notch glucosylation does not affect Notch ligand binding. Required during early development to promote gastrulation- acts by mediating O- g [...] | 0.582 |
PATE1 | AGR3 | ENSP00000307164 | ENSP00000308606 | Prostate and testis expressed 1; Belongs to the PATE family | Anterior gradient protein 3; Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells; Belongs to the AGR family | 0.552 |
PATE1 | FAM172A | ENSP00000307164 | ENSP00000379294 | Prostate and testis expressed 1; Belongs to the PATE family | Protein FAM172A; Family with sequence similarity 172 member A; Belongs to the UPF0528 family | 0.580 |
PATE1 | FKBP7 | ENSP00000307164 | ENSP00000413152 | Prostate and testis expressed 1; Belongs to the PATE family | Peptidylprolyl isomerase; EF-hand domain containing | 0.567 |
PATE1 | PATE2 | ENSP00000307164 | ENSP00000351325 | Prostate and testis expressed 1; Belongs to the PATE family | Prostate and testis expressed 2; LY6/PLAUR domain containing | 0.700 |
PATE1 | PATE3 | ENSP00000307164 | ENSP00000395505 | Prostate and testis expressed 1; Belongs to the PATE family | Prostate and testis expressed 3; Belongs to the PATE family | 0.711 |