• Version:
  • 11.0 [archived version]
STRINGSTRING
C1orf141 C1orf141 SATL1 SATL1 CCDC116 CCDC116 ACTL9 ACTL9 SHCBP1L SHCBP1L RBM44 RBM44 C8orf74 C8orf74 RP1L1 RP1L1 PRSS55 PRSS55 MORN2 MORN2 DEFB104B DEFB104B
"C8orf74" - Uncharacterized protein C8orf74 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
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Textmining
[Homology]
Score
C8orf74Uncharacterized protein C8orf74; Chromosome 8 open reading frame 74 (294 aa)    
Predicted Functional Partners:
C1orf141
Uncharacterized protein C1orf141; Chromosome 1 open reading frame 141 (400 aa)
     
   
  0.734
SATL1
Spermidine/spermine N1-acetyl transferase like 1; GCN5 related N-acetyltransferases (632 aa)
           
  0.709
MORN2
MORN repeat-containing protein 2; Might have a role in spermatogenesis (79 aa)
       
      0.685
SHCBP1L
Testicular spindle-associated protein SHCBP1L; Testis-specific spindle-associated factor that plays a role in spermatogenesis. In association with HSPA2, participates in the maintenance of spindle integrity during meiosis in male germ cells (653 aa)
     
   
  0.657
ACTL9
Actin-like protein 9; Actin related proteins (416 aa)
     
   
  0.583
PRSS55
Serine protease 55; Probable serine protease (352 aa)
           
  0.580
RBM44
RNA-binding protein 44; Component of intercellular bridges during meiosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells. Not required for fertility (By similarity); RNA binding motif containing (1052 aa)
           
  0.558
CCDC116
Coiled-coil domain containing 116 (613 aa)
           
  0.501
RP1L1
Retinitis pigmentosa 1-like 1 protein; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity); Doublecortin superfamily (2400 aa)
           
  0.491
DEFB104B
Beta-defensin 104; Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103; Belongs to the beta-defensin family (72 aa)
           
  0.473
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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