FAM151A protein (human) - STRING database

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FAM151A

Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family (585 aa)

Predicted Functional Partners:

STOX2

0.754

ARL14

0.696

MUC20

0.534

TMEM213

0.486

CDHR5

0.471

ALDH8A1

0.461

LYPD1

0.461

SLC6A19

0.454

SLC5A2

0.435

OR51E1

0.422

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH8A1	FAM151A	ENSP00000265605	ENSP00000306888	Aldehyde dehydrogenase family 8 member A1; Converts 9-cis-retinal to 9-cis-retinoic acid. Has lower activity towards 13-cis-retinal. Has much lower activity towards all-trans-retinal. Has highest activity with benzaldehyde and decanal (in vitro). Has a preference for NAD, but shows considerable activity with NADP (in vitro)	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	0.461
ARL14	FAM151A	ENSP00000323847	ENSP00000306888	ADP-ribosylation factor-like protein 14; GTPase that recruits MYO1E to MHC class II-containing vesicles via the effector protein ARL14EP and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells; ARF GTPase family	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	0.696
ARL14	STOX2	ENSP00000323847	ENSP00000311257	ADP-ribosylation factor-like protein 14; GTPase that recruits MYO1E to MHC class II-containing vesicles via the effector protein ARL14EP and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells; ARF GTPase family	Storkhead-box protein 2; Storkhead box 2	0.653
CDHR5	FAM151A	ENSP00000351118	ENSP00000306888	Cadherin-related family member 5; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR2 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation; Cadherin related	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	0.471
FAM151A	ALDH8A1	ENSP00000306888	ENSP00000265605	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	Aldehyde dehydrogenase family 8 member A1; Converts 9-cis-retinal to 9-cis-retinoic acid. Has lower activity towards 13-cis-retinal. Has much lower activity towards all-trans-retinal. Has highest activity with benzaldehyde and decanal (in vitro). Has a preference for NAD, but shows considerable activity with NADP (in vitro)	0.461
FAM151A	ARL14	ENSP00000306888	ENSP00000323847	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	ADP-ribosylation factor-like protein 14; GTPase that recruits MYO1E to MHC class II-containing vesicles via the effector protein ARL14EP and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells; ARF GTPase family	0.696
FAM151A	CDHR5	ENSP00000306888	ENSP00000351118	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	Cadherin-related family member 5; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR2 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation; Cadherin related	0.471
FAM151A	LYPD1	ENSP00000306888	ENSP00000380605	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	Ly6/PLAUR domain-containing protein 1; Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro increases receptor desensitization and decreases affinity for ACh of alpha- 4-beta-2-containing nAChRs. May play a role in the intracellular trafficking of alpha-4-beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface. May be involved in the control of anxiety; LY6/PLAUR domain containing	0.461
FAM151A	MUC20	ENSP00000306888	ENSP00000414350	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	Mucin-20; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression; Mucins	0.534
FAM151A	OR51E1	ENSP00000306888	ENSP00000380155	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	Olfactory receptor 51E1; Odorant receptor; Olfactory receptors, family 51	0.422
FAM151A	SLC5A2	ENSP00000306888	ENSP00000327943	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	Sodium/glucose cotransporter 2; Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1-1; Solute carriers	0.435
FAM151A	SLC6A19	ENSP00000306888	ENSP00000305302	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	Sodium-dependent neutral amino acid transporter B(0)AT1; Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells. This uptake is sodium-dependent and chloride- independent; Belongs to the sodium-neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A19 subfamily	0.454
FAM151A	STOX2	ENSP00000306888	ENSP00000311257	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	Storkhead-box protein 2; Storkhead box 2	0.754
FAM151A	TMEM213	ENSP00000306888	ENSP00000390407	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	Transmembrane protein 213	0.486
LYPD1	FAM151A	ENSP00000380605	ENSP00000306888	Ly6/PLAUR domain-containing protein 1; Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro increases receptor desensitization and decreases affinity for ACh of alpha- 4-beta-2-containing nAChRs. May play a role in the intracellular trafficking of alpha-4-beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface. May be involved in the control of anxiety; LY6/PLAUR domain containing	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	0.461
MUC20	FAM151A	ENSP00000414350	ENSP00000306888	Mucin-20; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression; Mucins	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	0.534
MUC20	STOX2	ENSP00000414350	ENSP00000311257	Mucin-20; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression; Mucins	Storkhead-box protein 2; Storkhead box 2	0.507
OR51E1	FAM151A	ENSP00000380155	ENSP00000306888	Olfactory receptor 51E1; Odorant receptor; Olfactory receptors, family 51	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	0.422
SLC5A2	FAM151A	ENSP00000327943	ENSP00000306888	Sodium/glucose cotransporter 2; Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1-1; Solute carriers	Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family	0.435
SLC5A2	SLC6A19	ENSP00000327943	ENSP00000305302	Sodium/glucose cotransporter 2; Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1-1; Solute carriers	Sodium-dependent neutral amino acid transporter B(0)AT1; Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells. This uptake is sodium-dependent and chloride- independent; Belongs to the sodium-neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A19 subfamily	0.531

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