| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BLZF1 | ZNF565 | ENSP00000356782 | ENSP00000306869 | Golgin-45; Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.557 |
| CITED4 | ZNF565 | ENSP00000361721 | ENSP00000306869 | Cbp/p300-interacting transactivator 4; Acts as transcriptional coactivator for TFAP2/AP-2. Enhances estrogen-dependent transactivation mediated by estrogen receptors. May function as an inhibitor of transactivation by HIF1A by disrupting HIF1A interaction with CREBBP. May be involved in regulation of gene expression during development and differentiation of blood cells, endothelial cells and mammary epithelial cells; Belongs to the CITED family | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.574 |
| ISL2 | ZNF565 | ENSP00000290759 | ENSP00000306869 | Insulin gene enhancer protein ISL-2; Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways; LIM class homeoboxes | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.515 |
| IVNS1ABP | ZNF565 | ENSP00000356468 | ENSP00000306869 | Influenza virus NS1A-binding protein; Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may [...] | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.508 |
| PINX1 | ZNF565 | ENSP00000318966 | ENSP00000306869 | PIN2/TERF1-interacting telomerase inhibitor 1; Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor; Belongs to the PINX1 family | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.514 |
| PPIH | TAF6 | ENSP00000306614 | ENSP00000399982 | Peptidyl-prolyl cis-trans isomerase H; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. May act as a chaperone; Cyclophilin peptidylprolyl isomerases | Transcription initiation factor TFIID subunit 6; TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF6 family | 0.560 |
| PPIH | ZNF565 | ENSP00000306614 | ENSP00000306869 | Peptidyl-prolyl cis-trans isomerase H; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. May act as a chaperone; Cyclophilin peptidylprolyl isomerases | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.567 |
| TAF6 | PPIH | ENSP00000399982 | ENSP00000306614 | Transcription initiation factor TFIID subunit 6; TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF6 family | Peptidyl-prolyl cis-trans isomerase H; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. May act as a chaperone; Cyclophilin peptidylprolyl isomerases | 0.560 |
| TAF6 | ZNF565 | ENSP00000399982 | ENSP00000306869 | Transcription initiation factor TFIID subunit 6; TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF6 family | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.517 |
| TMC4 | ZNF565 | ENSP00000477627 | ENSP00000306869 | Transmembrane channel-like protein 4; Probable ion channel; Transmembrane channel likes | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.536 |
| TRIM28 | ZNF565 | ENSP00000253024 | ENSP00000306869 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.903 |
| ZNF207 | ZNF565 | ENSP00000378165 | ENSP00000306869 | BUB3-interacting and GLEBS motif-containing protein ZNF207; Kinetochore- and microtubule-binding protein that plays a key role in spindle assembly. ZNF207/BuGZ is mainly composed of disordered low-complexity regions and undergoes phase transition or coacervation to form temperature-dependent liquid droplets. Coacervation promotes microtubule bundling and concentrates tubulin, promoting microtubule polymerization and assembly of spindle and spindle matrix by concentrating its building blocks. Also acts as a regulator of mitotic chromosome alignment by mediating the stability and kinetoc [...] | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.556 |
| ZNF565 | BLZF1 | ENSP00000306869 | ENSP00000356782 | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Golgin-45; Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface | 0.557 |
| ZNF565 | CITED4 | ENSP00000306869 | ENSP00000361721 | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Cbp/p300-interacting transactivator 4; Acts as transcriptional coactivator for TFAP2/AP-2. Enhances estrogen-dependent transactivation mediated by estrogen receptors. May function as an inhibitor of transactivation by HIF1A by disrupting HIF1A interaction with CREBBP. May be involved in regulation of gene expression during development and differentiation of blood cells, endothelial cells and mammary epithelial cells; Belongs to the CITED family | 0.574 |
| ZNF565 | ISL2 | ENSP00000306869 | ENSP00000290759 | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Insulin gene enhancer protein ISL-2; Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways; LIM class homeoboxes | 0.515 |
| ZNF565 | IVNS1ABP | ENSP00000306869 | ENSP00000356468 | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Influenza virus NS1A-binding protein; Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may [...] | 0.508 |
| ZNF565 | PINX1 | ENSP00000306869 | ENSP00000318966 | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | PIN2/TERF1-interacting telomerase inhibitor 1; Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor; Belongs to the PINX1 family | 0.514 |
| ZNF565 | PPIH | ENSP00000306869 | ENSP00000306614 | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Peptidyl-prolyl cis-trans isomerase H; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. May act as a chaperone; Cyclophilin peptidylprolyl isomerases | 0.567 |
| ZNF565 | TAF6 | ENSP00000306869 | ENSP00000399982 | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Transcription initiation factor TFIID subunit 6; TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TIIFD is multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF6 family | 0.517 |
| ZNF565 | TMC4 | ENSP00000306869 | ENSP00000477627 | Zinc finger protein 565; May be involved in transcriptional regulation; Zinc fingers C2H2-type | Transmembrane channel-like protein 4; Probable ion channel; Transmembrane channel likes | 0.536 |
