| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CAMTA1 | CASZ1 | ENSP00000306522 | ENSP00000366221 | Calmodulin-binding transcription activator 1; Transcriptional activator. May act as a tumor suppressor; Belongs to the CAMTA family | Zinc finger protein castor homolog 1; Transcriptional activator. Involved in vascular assembly and morphogenesis through direct transcriptional regulation of EGFL7; Zinc fingers C2H2-type | 0.575 |
| CAMTA1 | COQ4 | ENSP00000306522 | ENSP00000300452 | Calmodulin-binding transcription activator 1; Transcriptional activator. May act as a tumor suppressor; Belongs to the CAMTA family | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides | 0.663 |
| CAMTA1 | DEDD | ENSP00000306522 | ENSP00000356985 | Calmodulin-binding transcription activator 1; Transcriptional activator. May act as a tumor suppressor; Belongs to the CAMTA family | Death effector domain-containing protein; A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity); Death effector domain containing | 0.583 |
| CAMTA1 | DIXDC1 | ENSP00000306522 | ENSP00000394352 | Calmodulin-binding transcription activator 1; Transcriptional activator. May act as a tumor suppressor; Belongs to the CAMTA family | Dixin; Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2; Belongs to the DIXDC1 family | 0.656 |
| CAMTA1 | FBXL4 | ENSP00000306522 | ENSP00000358247 | Calmodulin-binding transcription activator 1; Transcriptional activator. May act as a tumor suppressor; Belongs to the CAMTA family | F-box and leucine rich repeat protein 4 | 0.580 |
| CAMTA1 | FBXW2 | ENSP00000306522 | ENSP00000476369 | Calmodulin-binding transcription activator 1; Transcriptional activator. May act as a tumor suppressor; Belongs to the CAMTA family | F-box/WD repeat-containing protein 2; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex; F-box and WD repeat domain containing | 0.583 |
| CAMTA1 | IMPAD1 | ENSP00000306522 | ENSP00000262644 | Calmodulin-binding transcription activator 1; Transcriptional activator. May act as a tumor suppressor; Belongs to the CAMTA family | Inositol monophosphatase 3; May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3’,5’-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation | 0.595 |
| CAMTA1 | NPPA | ENSP00000306522 | ENSP00000365663 | Calmodulin-binding transcription activator 1; Transcriptional activator. May act as a tumor suppressor; Belongs to the CAMTA family | Natriuretic peptides A; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3; Belongs to the natriuretic peptide family | 0.752 |
| CAMTA1 | TFE3 | ENSP00000306522 | ENSP00000314129 | Calmodulin-binding transcription activator 1; Transcriptional activator. May act as a tumor suppressor; Belongs to the CAMTA family | Transcription factor E3; Transcription factor that specifically recognizes and binds E-box sequences (5’-CANNTG-3’). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site; Basic helix-lo [...] | 0.641 |
| CAMTA1 | WWTR1 | ENSP00000306522 | ENSP00000419465 | Calmodulin-binding transcription activator 1; Transcriptional activator. May act as a tumor suppressor; Belongs to the CAMTA family | WW domain-containing transcription regulator protein 1; Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. WWTR1 enhances [...] | 0.732 |
| CASZ1 | CAMTA1 | ENSP00000366221 | ENSP00000306522 | Zinc finger protein castor homolog 1; Transcriptional activator. Involved in vascular assembly and morphogenesis through direct transcriptional regulation of EGFL7; Zinc fingers C2H2-type | Calmodulin-binding transcription activator 1; Transcriptional activator. May act as a tumor suppressor; Belongs to the CAMTA family | 0.575 |
| COQ4 | CAMTA1 | ENSP00000300452 | ENSP00000306522 | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides | Calmodulin-binding transcription activator 1; Transcriptional activator. May act as a tumor suppressor; Belongs to the CAMTA family | 0.663 |
| COQ4 | DEDD | ENSP00000300452 | ENSP00000356985 | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides | Death effector domain-containing protein; A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity); Death effector domain containing | 0.665 |
| COQ4 | DIXDC1 | ENSP00000300452 | ENSP00000394352 | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides | Dixin; Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2; Belongs to the DIXDC1 family | 0.675 |
| DEDD | CAMTA1 | ENSP00000356985 | ENSP00000306522 | Death effector domain-containing protein; A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity); Death effector domain containing | Calmodulin-binding transcription activator 1; Transcriptional activator. May act as a tumor suppressor; Belongs to the CAMTA family | 0.583 |
| DEDD | COQ4 | ENSP00000356985 | ENSP00000300452 | Death effector domain-containing protein; A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity); Death effector domain containing | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides | 0.665 |
| DEDD | DIXDC1 | ENSP00000356985 | ENSP00000394352 | Death effector domain-containing protein; A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity); Death effector domain containing | Dixin; Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2; Belongs to the DIXDC1 family | 0.655 |
| DIXDC1 | CAMTA1 | ENSP00000394352 | ENSP00000306522 | Dixin; Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2; Belongs to the DIXDC1 family | Calmodulin-binding transcription activator 1; Transcriptional activator. May act as a tumor suppressor; Belongs to the CAMTA family | 0.656 |
| DIXDC1 | COQ4 | ENSP00000394352 | ENSP00000300452 | Dixin; Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2; Belongs to the DIXDC1 family | Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides | 0.675 |
| DIXDC1 | DEDD | ENSP00000394352 | ENSP00000356985 | Dixin; Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2; Belongs to the DIXDC1 family | Death effector domain-containing protein; A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity); Death effector domain containing | 0.655 |
