| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FGF13 | NUDT6 | ENSP00000322390 | ENSP00000306070 | Fibroblast growth factor 13; Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate to the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus; Belongs to the heparin-binding growth factors family | Nucleoside diphosphate-linked moiety X motif 6; May contribute to the regulation of cell proliferation; Belongs to the Nudix hydrolase family | 0.650 |
| FGF2 | NUDT6 | ENSP00000264498 | ENSP00000306070 | Fibroblast growth factor 2; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Can induce angiogenesis; Belongs to the heparin-binding growth factors family | Nucleoside diphosphate-linked moiety X motif 6; May contribute to the regulation of cell proliferation; Belongs to the Nudix hydrolase family | 0.720 |
| GYG1 | KCNK1 | ENSP00000340736 | ENSP00000355580 | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase; Glycosyltransferase family 8 | Potassium channel subfamily K member 1; Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues. Forms dimeric channels through which potassium ions pass in accordance with their electrochemical gradient. The channel is selective for K(+) ions at physiological potassium concentrations and at neutral pH, but becomes permeable to Na(+) at subphysiological K(+) levels and upon acidification of the extracellular medium. The homodimer has very low potassium [...] | 0.407 |
| GYG1 | KCNK15 | ENSP00000340736 | ENSP00000361952 | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase; Glycosyltransferase family 8 | Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K | 0.758 |
| GYG1 | KCNK3 | ENSP00000340736 | ENSP00000306275 | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase; Glycosyltransferase family 8 | Potassium channel subfamily K member 3; pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family | 0.754 |
| GYG1 | KCNK9 | ENSP00000340736 | ENSP00000430676 | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase; Glycosyltransferase family 8 | Potassium channel subfamily K member 9; pH-dependent, voltage-insensitive, background potassium channel protein; Potassium two pore domain channel subfamily K | 0.807 |
| GYG1 | NUDT6 | ENSP00000340736 | ENSP00000306070 | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase; Glycosyltransferase family 8 | Nucleoside diphosphate-linked moiety X motif 6; May contribute to the regulation of cell proliferation; Belongs to the Nudix hydrolase family | 0.884 |
| KCNK1 | GYG1 | ENSP00000355580 | ENSP00000340736 | Potassium channel subfamily K member 1; Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues. Forms dimeric channels through which potassium ions pass in accordance with their electrochemical gradient. The channel is selective for K(+) ions at physiological potassium concentrations and at neutral pH, but becomes permeable to Na(+) at subphysiological K(+) levels and upon acidification of the extracellular medium. The homodimer has very low potassium [...] | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase; Glycosyltransferase family 8 | 0.407 |
| KCNK1 | NUDT6 | ENSP00000355580 | ENSP00000306070 | Potassium channel subfamily K member 1; Ion channel that contributes to passive transmembrane potassium transport and to the regulation of the resting membrane potential in brain astrocytes, but also in kidney and in other tissues. Forms dimeric channels through which potassium ions pass in accordance with their electrochemical gradient. The channel is selective for K(+) ions at physiological potassium concentrations and at neutral pH, but becomes permeable to Na(+) at subphysiological K(+) levels and upon acidification of the extracellular medium. The homodimer has very low potassium [...] | Nucleoside diphosphate-linked moiety X motif 6; May contribute to the regulation of cell proliferation; Belongs to the Nudix hydrolase family | 0.753 |
| KCNK15 | GYG1 | ENSP00000361952 | ENSP00000340736 | Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase; Glycosyltransferase family 8 | 0.758 |
| KCNK15 | NUDT6 | ENSP00000361952 | ENSP00000306070 | Potassium channel subfamily K member 15; Probable potassium channel subunit. No channel activity observed in heterologous systems. May need to associate with another protein to form a functional channel; Potassium two pore domain channel subfamily K | Nucleoside diphosphate-linked moiety X motif 6; May contribute to the regulation of cell proliferation; Belongs to the Nudix hydrolase family | 0.756 |
| KCNK2 | NUDT6 | ENSP00000394033 | ENSP00000306070 | Potassium channel subfamily K member 2; Ion channel that contributes to passive transmembrane potassium transport. Reversibly converts between a voltage-insensitive potassium leak channel and a voltage- dependent outward rectifying potassium channel in a phosphorylation-dependent manner. In astrocytes, forms mostly heterodimeric potassium channels with KCNK1, with only a minor proportion of functional channels containing homodimeric KCNK2. In astrocytes, the heterodimer formed by KCNK1 and KCNK2 is required for rapid glutamate release in response to activation of G-protein coupled rece [...] | Nucleoside diphosphate-linked moiety X motif 6; May contribute to the regulation of cell proliferation; Belongs to the Nudix hydrolase family | 0.800 |
| KCNK3 | GYG1 | ENSP00000306275 | ENSP00000340736 | Potassium channel subfamily K member 3; pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase; Glycosyltransferase family 8 | 0.754 |
| KCNK3 | KCNK9 | ENSP00000306275 | ENSP00000430676 | Potassium channel subfamily K member 3; pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family | Potassium channel subfamily K member 9; pH-dependent, voltage-insensitive, background potassium channel protein; Potassium two pore domain channel subfamily K | 0.907 |
| KCNK3 | NUDT6 | ENSP00000306275 | ENSP00000306070 | Potassium channel subfamily K member 3; pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family | Nucleoside diphosphate-linked moiety X motif 6; May contribute to the regulation of cell proliferation; Belongs to the Nudix hydrolase family | 0.802 |
| KCNK6 | NUDT6 | ENSP00000263372 | ENSP00000306070 | Potassium channel subfamily K member 6; Exhibits outward rectification in a physiological K(+) gradient and mild inward rectification in symmetrical K(+) conditions; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family | Nucleoside diphosphate-linked moiety X motif 6; May contribute to the regulation of cell proliferation; Belongs to the Nudix hydrolase family | 0.756 |
| KCNK7 | NUDT6 | ENSP00000344820 | ENSP00000306070 | Potassium channel subfamily K member 7; Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as yet unknown partner in order to reach the plasma membrane; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family | Nucleoside diphosphate-linked moiety X motif 6; May contribute to the regulation of cell proliferation; Belongs to the Nudix hydrolase family | 0.756 |
| KCNK9 | GYG1 | ENSP00000430676 | ENSP00000340736 | Potassium channel subfamily K member 9; pH-dependent, voltage-insensitive, background potassium channel protein; Potassium two pore domain channel subfamily K | Glycogenin-1; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase; Glycosyltransferase family 8 | 0.807 |
| KCNK9 | KCNK3 | ENSP00000430676 | ENSP00000306275 | Potassium channel subfamily K member 9; pH-dependent, voltage-insensitive, background potassium channel protein; Potassium two pore domain channel subfamily K | Potassium channel subfamily K member 3; pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family | 0.907 |
| KCNK9 | NUDT6 | ENSP00000430676 | ENSP00000306070 | Potassium channel subfamily K member 9; pH-dependent, voltage-insensitive, background potassium channel protein; Potassium two pore domain channel subfamily K | Nucleoside diphosphate-linked moiety X motif 6; May contribute to the regulation of cell proliferation; Belongs to the Nudix hydrolase family | 0.804 |
