OTUD7A protein (human) - STRING database

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OTUD7A

OTU domain-containing protein 7A; Has deubiquitinating activity towards ’Lys-11’-linked polyubiquitin chains; Belongs to the peptidase C64 family (926 aa)

Predicted Functional Partners:

UBA52

0.971

RPS27A

0.970

UBC

0.957

UBB

0.933

MTMR10

0.827

CHRFAM7A

0.807

OTUD3

0.720

ZNF501

0.719

ENSG00000197054

0.719

ZNF569

0.719

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHRFAM7A	MTMR10	ENSP00000299847	ENSP00000402537	CHRNA7-FAM7A fusion protein; CHRNA7 fusion; Belongs to the ligand-gated ion channel (TC 1.A.9) family	Myotubularin-related protein 10; Probable pseudophosphatase. Contains a Glu residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase (Potential); Myotubularins	0.693
CHRFAM7A	OTUD7A	ENSP00000299847	ENSP00000305926	CHRNA7-FAM7A fusion protein; CHRNA7 fusion; Belongs to the ligand-gated ion channel (TC 1.A.9) family	OTU domain-containing protein 7A; Has deubiquitinating activity towards ’Lys-11’-linked polyubiquitin chains; Belongs to the peptidase C64 family	0.807
ENSG00000197054	OTUD7A	ENSP00000369774	ENSP00000305926	Zinc finger protein 763; May be involved in transcriptional regulation; Zinc fingers C2H2-type	OTU domain-containing protein 7A; Has deubiquitinating activity towards ’Lys-11’-linked polyubiquitin chains; Belongs to the peptidase C64 family	0.719
ENSG00000197054	UBC	ENSP00000369774	ENSP00000441543	Zinc finger protein 763; May be involved in transcriptional regulation; Zinc fingers C2H2-type	Polyubiquitin-C; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be involved in DNA repair; [...]	0.583
MTMR10	CHRFAM7A	ENSP00000402537	ENSP00000299847	Myotubularin-related protein 10; Probable pseudophosphatase. Contains a Glu residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase (Potential); Myotubularins	CHRNA7-FAM7A fusion protein; CHRNA7 fusion; Belongs to the ligand-gated ion channel (TC 1.A.9) family	0.693
MTMR10	OTUD7A	ENSP00000402537	ENSP00000305926	Myotubularin-related protein 10; Probable pseudophosphatase. Contains a Glu residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase (Potential); Myotubularins	OTU domain-containing protein 7A; Has deubiquitinating activity towards ’Lys-11’-linked polyubiquitin chains; Belongs to the peptidase C64 family	0.827
OTUD3	OTUD7A	ENSP00000364261	ENSP00000305926	OTU domain-containing protein 3; Deubiquitinating enzyme that hydrolyzes ’Lys-6’- and ’Lys-11’-linked polyubiquitin. Also hydrolyzes heterotypic (mixed and branched) and homotypic chains; OTU domain containing	OTU domain-containing protein 7A; Has deubiquitinating activity towards ’Lys-11’-linked polyubiquitin chains; Belongs to the peptidase C64 family	0.720
OTUD3	RPS27A	ENSP00000364261	ENSP00000272317	OTU domain-containing protein 3; Deubiquitinating enzyme that hydrolyzes ’Lys-6’- and ’Lys-11’-linked polyubiquitin. Also hydrolyzes heterotypic (mixed and branched) and homotypic chains; OTU domain containing	Ubiquitin-40S ribosomal protein S27a; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be inv [...]	0.904
OTUD3	UBA52	ENSP00000364261	ENSP00000388107	OTU domain-containing protein 3; Deubiquitinating enzyme that hydrolyzes ’Lys-6’- and ’Lys-11’-linked polyubiquitin. Also hydrolyzes heterotypic (mixed and branched) and homotypic chains; OTU domain containing	Ubiquitin-60S ribosomal protein L40; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be invo [...]	0.900
OTUD3	UBB	ENSP00000364261	ENSP00000304697	OTU domain-containing protein 3; Deubiquitinating enzyme that hydrolyzes ’Lys-6’- and ’Lys-11’-linked polyubiquitin. Also hydrolyzes heterotypic (mixed and branched) and homotypic chains; OTU domain containing	Polyubiquitin-B; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be involved in DNA repair; [...]	0.900
OTUD3	UBC	ENSP00000364261	ENSP00000441543	OTU domain-containing protein 3; Deubiquitinating enzyme that hydrolyzes ’Lys-6’- and ’Lys-11’-linked polyubiquitin. Also hydrolyzes heterotypic (mixed and branched) and homotypic chains; OTU domain containing	Polyubiquitin-C; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be involved in DNA repair; [...]	0.945
OTUD7A	CHRFAM7A	ENSP00000305926	ENSP00000299847	OTU domain-containing protein 7A; Has deubiquitinating activity towards ’Lys-11’-linked polyubiquitin chains; Belongs to the peptidase C64 family	CHRNA7-FAM7A fusion protein; CHRNA7 fusion; Belongs to the ligand-gated ion channel (TC 1.A.9) family	0.807
OTUD7A	ENSG00000197054	ENSP00000305926	ENSP00000369774	OTU domain-containing protein 7A; Has deubiquitinating activity towards ’Lys-11’-linked polyubiquitin chains; Belongs to the peptidase C64 family	Zinc finger protein 763; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.719
OTUD7A	MTMR10	ENSP00000305926	ENSP00000402537	OTU domain-containing protein 7A; Has deubiquitinating activity towards ’Lys-11’-linked polyubiquitin chains; Belongs to the peptidase C64 family	Myotubularin-related protein 10; Probable pseudophosphatase. Contains a Glu residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase (Potential); Myotubularins	0.827
OTUD7A	OTUD3	ENSP00000305926	ENSP00000364261	OTU domain-containing protein 7A; Has deubiquitinating activity towards ’Lys-11’-linked polyubiquitin chains; Belongs to the peptidase C64 family	OTU domain-containing protein 3; Deubiquitinating enzyme that hydrolyzes ’Lys-6’- and ’Lys-11’-linked polyubiquitin. Also hydrolyzes heterotypic (mixed and branched) and homotypic chains; OTU domain containing	0.720
OTUD7A	RPS27A	ENSP00000305926	ENSP00000272317	OTU domain-containing protein 7A; Has deubiquitinating activity towards ’Lys-11’-linked polyubiquitin chains; Belongs to the peptidase C64 family	Ubiquitin-40S ribosomal protein S27a; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be inv [...]	0.970
OTUD7A	UBA52	ENSP00000305926	ENSP00000388107	OTU domain-containing protein 7A; Has deubiquitinating activity towards ’Lys-11’-linked polyubiquitin chains; Belongs to the peptidase C64 family	Ubiquitin-60S ribosomal protein L40; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be invo [...]	0.971
OTUD7A	UBB	ENSP00000305926	ENSP00000304697	OTU domain-containing protein 7A; Has deubiquitinating activity towards ’Lys-11’-linked polyubiquitin chains; Belongs to the peptidase C64 family	Polyubiquitin-B; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be involved in DNA repair; [...]	0.933
OTUD7A	UBC	ENSP00000305926	ENSP00000441543	OTU domain-containing protein 7A; Has deubiquitinating activity towards ’Lys-11’-linked polyubiquitin chains; Belongs to the peptidase C64 family	Polyubiquitin-C; Ubiquitin- Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked- Lys-6-linked may be involved in DNA repair; [...]	0.957
OTUD7A	ZNF501	ENSP00000305926	ENSP00000482632	OTU domain-containing protein 7A; Has deubiquitinating activity towards ’Lys-11’-linked polyubiquitin chains; Belongs to the peptidase C64 family	Zinc finger protein 501; May be involved in transcriptional regulation; Zinc fingers C2H2-type	0.719

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