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  • 11.0 [archived version]
STRINGSTRING
MREG MREG CYLC1 CYLC1 ZNF81 ZNF81 TEX11 TEX11 ZNF182 ZNF182 SPACA5 SPACA5 ZNF630 ZNF630 TCP11 TCP11 ZNF212 ZNF212 ACTRT1 ACTRT1 SPRYD4 SPRYD4
"SPACA5" - Sperm acrosome associated 5 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
Coexpression
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[Homology]
Score
SPACA5Sperm acrosome associated 5; Belongs to the glycosyl hydrolase 22 family (159 aa)    
Predicted Functional Partners:
ZNF630
Zinc finger protein 630; May be involved in transcriptional regulation; Zinc fingers C2H2-type (657 aa)
            
  0.725
CYLC1
Cylicin-1; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation (651 aa)
      
   
  0.642
ZNF212
Zinc finger protein 212; May be involved in transcriptional regulation; Zinc fingers C2H2-type (495 aa)
            
  0.630
SPRYD4
SPRY domain containing 4 (207 aa)
            
  0.605
ZNF182
Zinc finger protein 182; May be involved in transcriptional regulation; Zinc fingers C2H2-type (639 aa)
            
  0.571
TCP11
T-complex protein 11 homolog; Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization-promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway; Belongs to the TCP11 family (516 aa)
            
  0.551
TEX11
Testis-expressed protein 11; Regulator of crossing-over during meiosis. Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers (By similarity) (940 aa)
            
  0.547
ZNF81
Zinc finger protein 81; May be involved in transcriptional regulation; X-linked mental retardation (661 aa)
            
  0.543
ACTRT1
Actin related protein T1 (376 aa)
      
   
  0.536
MREG
Melanoregulin; Plays a role in the incorporation of pigments into hair. May function in membrane fusion and regulate the biogenesis of disk membranes of photoreceptor rod cells (By similarity) (214 aa)
            
  0.525
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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