| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CDHR2 | GPRIN1 | ENSP00000424565 | ENSP00000305839 | Cadherin-related family member 2; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells; Cadhe [...] | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | 0.755 |
| CDHR2 | NSD1 | ENSP00000424565 | ENSP00000395929 | Cadherin-related family member 2; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells; Cadhe [...] | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific; Histone methyltransferase. Preferentially methylates ’Lys-36’ of histone H3 and ’Lys-20’ of histone H4 (in vitro). Transcriptional intermediary factor capable of both negatively or positively influencing transcription, depending on the cellular context; Lysine methyltransferases | 0.654 |
| CDHR2 | RAB24 | ENSP00000424565 | ENSP00000304376 | Cadherin-related family member 2; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells; Cadhe [...] | Ras-related protein Rab-24; May be involved in autophagy-related processes; Belongs to the small GTPase superfamily. Rab family | 0.684 |
| CDHR2 | SPTBN2 | ENSP00000424565 | ENSP00000432568 | Cadherin-related family member 2; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells; Cadhe [...] | Spectrin beta chain, non-erythrocytic 2; Probably plays an important role in neuronal membrane skeleton; Belongs to the spectrin family | 0.523 |
| CEND1 | GPRIN1 | ENSP00000328336 | ENSP00000305839 | Cell cycle exit and neuronal differentiation protein 1; Involved in neuronal differentiation; Belongs to the CEND1 family | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | 0.627 |
| GNAZ | GPRIN1 | ENSP00000478892 | ENSP00000305839 | Guanine nucleotide-binding protein G(z) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | 0.761 |
| GPATCH8 | GPRIN1 | ENSP00000467556 | ENSP00000305839 | G-patch domain containing 8 | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | 0.597 |
| GPRIN1 | CDHR2 | ENSP00000305839 | ENSP00000424565 | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | Cadherin-related family member 2; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells; Cadhe [...] | 0.755 |
| GPRIN1 | CEND1 | ENSP00000305839 | ENSP00000328336 | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | Cell cycle exit and neuronal differentiation protein 1; Involved in neuronal differentiation; Belongs to the CEND1 family | 0.627 |
| GPRIN1 | GNAZ | ENSP00000305839 | ENSP00000478892 | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | Guanine nucleotide-binding protein G(z) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems | 0.761 |
| GPRIN1 | GPATCH8 | ENSP00000305839 | ENSP00000467556 | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | G-patch domain containing 8 | 0.597 |
| GPRIN1 | NSD1 | ENSP00000305839 | ENSP00000395929 | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific; Histone methyltransferase. Preferentially methylates ’Lys-36’ of histone H3 and ’Lys-20’ of histone H4 (in vitro). Transcriptional intermediary factor capable of both negatively or positively influencing transcription, depending on the cellular context; Lysine methyltransferases | 0.657 |
| GPRIN1 | OR1L6 | ENSP00000305839 | ENSP00000304235 | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | Olfactory receptor 1L6; Odorant receptor; Olfactory receptors, family 1 | 0.581 |
| GPRIN1 | PMEPA1 | ENSP00000305839 | ENSP00000345826 | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | Protein TMEPAI; Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may [...] | 0.572 |
| GPRIN1 | RAB24 | ENSP00000305839 | ENSP00000304376 | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | Ras-related protein Rab-24; May be involved in autophagy-related processes; Belongs to the small GTPase superfamily. Rab family | 0.690 |
| GPRIN1 | SPTBN2 | ENSP00000305839 | ENSP00000432568 | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | Spectrin beta chain, non-erythrocytic 2; Probably plays an important role in neuronal membrane skeleton; Belongs to the spectrin family | 0.575 |
| GPRIN1 | SRPK3 | ENSP00000305839 | ENSP00000359119 | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | SRSF protein kinase 3; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development (By similarity) | 0.724 |
| NSD1 | CDHR2 | ENSP00000395929 | ENSP00000424565 | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific; Histone methyltransferase. Preferentially methylates ’Lys-36’ of histone H3 and ’Lys-20’ of histone H4 (in vitro). Transcriptional intermediary factor capable of both negatively or positively influencing transcription, depending on the cellular context; Lysine methyltransferases | Cadherin-related family member 2; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR5 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. May also play a role in cell-cell adhesion and contact inhibition in epithelial cells; Cadhe [...] | 0.654 |
| NSD1 | GPRIN1 | ENSP00000395929 | ENSP00000305839 | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific; Histone methyltransferase. Preferentially methylates ’Lys-36’ of histone H3 and ’Lys-20’ of histone H4 (in vitro). Transcriptional intermediary factor capable of both negatively or positively influencing transcription, depending on the cellular context; Lysine methyltransferases | G protein-regulated inducer of neurite outgrowth 1; May be involved in neurite outgrowth | 0.657 |
| NSD1 | RAB24 | ENSP00000395929 | ENSP00000304376 | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific; Histone methyltransferase. Preferentially methylates ’Lys-36’ of histone H3 and ’Lys-20’ of histone H4 (in vitro). Transcriptional intermediary factor capable of both negatively or positively influencing transcription, depending on the cellular context; Lysine methyltransferases | Ras-related protein Rab-24; May be involved in autophagy-related processes; Belongs to the small GTPase superfamily. Rab family | 0.582 |
