| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATXN10 | C8orf37 | ENSP00000252934 | ENSP00000286688 | Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis; Armadillo-like helical domain containing | Protein C8orf37; Chromosome 8 open reading frame 37; Bardet-Biedl syndrome associated | 0.675 |
| ATXN10 | NXNL1 | ENSP00000252934 | ENSP00000305631 | Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis; Armadillo-like helical domain containing | Nucleoredoxin-like protein 1; May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods; Nucleoredoxin family | 0.672 |
| ATXN10 | SLC18A2 | ENSP00000252934 | ENSP00000298472 | Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis; Armadillo-like helical domain containing | Synaptic vesicular amine transporter; Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis; Belongs to the major facilitator superfamily. Vesicular transporter family | 0.628 |
| ATXN10 | TNNI1 | ENSP00000252934 | ENSP00000354488 | Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis; Armadillo-like helical domain containing | Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity | 0.643 |
| ATXN10 | TNNI3 | ENSP00000252934 | ENSP00000341838 | Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis; Armadillo-like helical domain containing | Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity | 0.627 |
| C8orf37 | ATXN10 | ENSP00000286688 | ENSP00000252934 | Protein C8orf37; Chromosome 8 open reading frame 37; Bardet-Biedl syndrome associated | Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis; Armadillo-like helical domain containing | 0.675 |
| C8orf37 | NXNL1 | ENSP00000286688 | ENSP00000305631 | Protein C8orf37; Chromosome 8 open reading frame 37; Bardet-Biedl syndrome associated | Nucleoredoxin-like protein 1; May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods; Nucleoredoxin family | 0.714 |
| C8orf37 | SLC18A2 | ENSP00000286688 | ENSP00000298472 | Protein C8orf37; Chromosome 8 open reading frame 37; Bardet-Biedl syndrome associated | Synaptic vesicular amine transporter; Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis; Belongs to the major facilitator superfamily. Vesicular transporter family | 0.642 |
| C8orf37 | TNNI1 | ENSP00000286688 | ENSP00000354488 | Protein C8orf37; Chromosome 8 open reading frame 37; Bardet-Biedl syndrome associated | Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity | 0.669 |
| C8orf37 | TNNI3 | ENSP00000286688 | ENSP00000341838 | Protein C8orf37; Chromosome 8 open reading frame 37; Bardet-Biedl syndrome associated | Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity | 0.510 |
| NXNL1 | ATXN10 | ENSP00000305631 | ENSP00000252934 | Nucleoredoxin-like protein 1; May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods; Nucleoredoxin family | Ataxin-10; Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis; Armadillo-like helical domain containing | 0.672 |
| NXNL1 | C8orf37 | ENSP00000305631 | ENSP00000286688 | Nucleoredoxin-like protein 1; May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods; Nucleoredoxin family | Protein C8orf37; Chromosome 8 open reading frame 37; Bardet-Biedl syndrome associated | 0.714 |
| NXNL1 | PAX4 | ENSP00000305631 | ENSP00000339906 | Nucleoredoxin-like protein 1; May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods; Nucleoredoxin family | Paired box protein Pax-4; Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity; PRD class homeoboxes and pseudogenes | 0.711 |
| NXNL1 | PDE6B | ENSP00000305631 | ENSP00000420295 | Nucleoredoxin-like protein 1; May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods; Nucleoredoxin family | Rod cGMP-specific 3’,5’-cyclic phosphodiesterase subunit beta; This protein participates in processes of transmission and amplification of the visual signal. Necessary for the formation of a functional phosphodiesterase holoenzyme; Belongs to the cyclic nucleotide phosphodiesterase family | 0.647 |
| NXNL1 | SLC18A2 | ENSP00000305631 | ENSP00000298472 | Nucleoredoxin-like protein 1; May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods; Nucleoredoxin family | Synaptic vesicular amine transporter; Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis; Belongs to the major facilitator superfamily. Vesicular transporter family | 0.639 |
| NXNL1 | SP3 | ENSP00000305631 | ENSP00000310301 | Nucleoredoxin-like protein 1; May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods; Nucleoredoxin family | Transcription factor Sp3; Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone- induction and house-keeping | 0.647 |
| NXNL1 | TNNI1 | ENSP00000305631 | ENSP00000354488 | Nucleoredoxin-like protein 1; May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods; Nucleoredoxin family | Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity | 0.666 |
| NXNL1 | TNNI3 | ENSP00000305631 | ENSP00000341838 | Nucleoredoxin-like protein 1; May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods; Nucleoredoxin family | Troponin I, cardiac muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity | 0.638 |
| NXNL1 | VSX1 | ENSP00000305631 | ENSP00000365899 | Nucleoredoxin-like protein 1; May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods; Nucleoredoxin family | Visual system homeobox 1; Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster. May regulate the activity of the LCR and the cone opsin genes at earlier stages of development; Belongs to the paired homeobox family | 0.805 |
| NXNL1 | VSX2 | ENSP00000305631 | ENSP00000261980 | Nucleoredoxin-like protein 1; May play a role in cone cell viability, slowing down cone degeneration, does not seem to play a role in degenerating rods; Nucleoredoxin family | Visual system homeobox 2; Plays a significant role in the specification and morphogenesis of the sensory retina. May also participate in the development of the cells of the inner nuclear layer, particularly bipolar cells (By similarity); Belongs to the paired homeobox family | 0.746 |
