node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYC1 | FAM195A | ENSP00000317159 | ENSP00000305138 | Cytochrome c1, heme protein, mitochondrial; This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain; Apoptosome | MAPK regulated corepressor interacting protein 2; Family with sequence similarity 195, member A | 0.673 |
CYC1 | NDUFS8 | ENSP00000317159 | ENSP00000315774 | Cytochrome c1, heme protein, mitochondrial; This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain; Apoptosome | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). May donate electrons to ubiquinone; NADH-ubiquinone oxidoreductase core subunits | 0.997 |
CYC1 | NDUFV1 | ENSP00000317159 | ENSP00000322450 | Cytochrome c1, heme protein, mitochondrial; This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain; Apoptosome | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) | 0.994 |
FAM127A | FAM195A | ENSP00000257013 | ENSP00000305138 | Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member A; Belongs to the FAM127 family | MAPK regulated corepressor interacting protein 2; Family with sequence similarity 195, member A | 0.569 |
FAM127A | ZNF280D | ENSP00000257013 | ENSP00000267807 | Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member A; Belongs to the FAM127 family | Zinc finger protein 280D; May function as a transcription factor | 0.473 |
FAM195A | CYC1 | ENSP00000305138 | ENSP00000317159 | MAPK regulated corepressor interacting protein 2; Family with sequence similarity 195, member A | Cytochrome c1, heme protein, mitochondrial; This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain; Apoptosome | 0.673 |
FAM195A | FAM127A | ENSP00000305138 | ENSP00000257013 | MAPK regulated corepressor interacting protein 2; Family with sequence similarity 195, member A | Retrotransposon Gag-like protein 8B; Family with sequence similarity 127, member A; Belongs to the FAM127 family | 0.569 |
FAM195A | GATB | ENSP00000305138 | ENSP00000263985 | MAPK regulated corepressor interacting protein 2; Family with sequence similarity 195, member A | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln) | 0.708 |
FAM195A | MTRNR2L11 | ENSP00000305138 | ENSP00000474861 | MAPK regulated corepressor interacting protein 2; Family with sequence similarity 195, member A | Humanin-like 11; Plays a role as a neuroprotective and antiapoptotic factor | 0.533 |
FAM195A | NDUFS8 | ENSP00000305138 | ENSP00000315774 | MAPK regulated corepressor interacting protein 2; Family with sequence similarity 195, member A | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). May donate electrons to ubiquinone; NADH-ubiquinone oxidoreductase core subunits | 0.695 |
FAM195A | NDUFV1 | ENSP00000305138 | ENSP00000322450 | MAPK regulated corepressor interacting protein 2; Family with sequence similarity 195, member A | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) | 0.680 |
FAM195A | PPRC1 | ENSP00000305138 | ENSP00000278070 | MAPK regulated corepressor interacting protein 2; Family with sequence similarity 195, member A | Peroxisome proliferator-activated receptor gamma coactivator-related protein 1; Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes; RNA binding motif containing | 0.504 |
FAM195A | SLC39A8 | ENSP00000305138 | ENSP00000378310 | MAPK regulated corepressor interacting protein 2; Family with sequence similarity 195, member A | Zinc transporter ZIP8; Acts as a manganese and zinc influx transporter. Plays a role in manganese reabsorption in the proximal tubule of the kidney and in manganese uptake into the brain; Belongs to the ZIP transporter (TC 2.A.5) family | 0.508 |
FAM195A | UHMK1 | ENSP00000305138 | ENSP00000420270 | MAPK regulated corepressor interacting protein 2; Family with sequence similarity 195, member A | Serine/threonine-protein kinase Kist; Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family | 0.575 |
FAM195A | ZNF280D | ENSP00000305138 | ENSP00000267807 | MAPK regulated corepressor interacting protein 2; Family with sequence similarity 195, member A | Zinc finger protein 280D; May function as a transcription factor | 0.712 |
GATB | FAM195A | ENSP00000263985 | ENSP00000305138 | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln) | MAPK regulated corepressor interacting protein 2; Family with sequence similarity 195, member A | 0.708 |
GATB | UHMK1 | ENSP00000263985 | ENSP00000420270 | Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln) | Serine/threonine-protein kinase Kist; Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family | 0.635 |
MTRNR2L11 | FAM195A | ENSP00000474861 | ENSP00000305138 | Humanin-like 11; Plays a role as a neuroprotective and antiapoptotic factor | MAPK regulated corepressor interacting protein 2; Family with sequence similarity 195, member A | 0.533 |
NDUFS8 | CYC1 | ENSP00000315774 | ENSP00000317159 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). May donate electrons to ubiquinone; NADH-ubiquinone oxidoreductase core subunits | Cytochrome c1, heme protein, mitochondrial; This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain; Apoptosome | 0.997 |
NDUFS8 | FAM195A | ENSP00000315774 | ENSP00000305138 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). May donate electrons to ubiquinone; NADH-ubiquinone oxidoreductase core subunits | MAPK regulated corepressor interacting protein 2; Family with sequence similarity 195, member A | 0.695 |