| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APBA2 | KLHL34 | ENSP00000453293 | ENSP00000368813 | Amyloid-beta A4 precursor protein-binding family A member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta; PDZ domain containing | Kelch-like protein 34; Kelch like family member 34; BTB domain containing | 0.439 |
| APBA2 | SMPX | ENSP00000453293 | ENSP00000368808 | Amyloid-beta A4 precursor protein-binding family A member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta; PDZ domain containing | Small muscular protein; Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair; Deafness associated genes | 0.451 |
| APBA2 | TMEM192 | ENSP00000453293 | ENSP00000305069 | Amyloid-beta A4 precursor protein-binding family A member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta; PDZ domain containing | Transmembrane protein 192 | 0.506 |
| ELFN1 | KLHL34 | ENSP00000456548 | ENSP00000368813 | Protein ELFN1; Postsynaptic protein that regulates circuit dynamics in the central nervous system by modulating the temporal dynamics of interneuron recruitment. Specifically present in excitatory synapses onto oriens-lacunosum molecular (OLM) interneurons and acts as a regulator of presynaptic release probability to direct the formation of highly facilitating pyramidal-OLM synapses (By similarity). Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Fibronectin type III domain containing | Kelch-like protein 34; Kelch like family member 34; BTB domain containing | 0.538 |
| ELFN1 | TMEM192 | ENSP00000456548 | ENSP00000305069 | Protein ELFN1; Postsynaptic protein that regulates circuit dynamics in the central nervous system by modulating the temporal dynamics of interneuron recruitment. Specifically present in excitatory synapses onto oriens-lacunosum molecular (OLM) interneurons and acts as a regulator of presynaptic release probability to direct the formation of highly facilitating pyramidal-OLM synapses (By similarity). Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Fibronectin type III domain containing | Transmembrane protein 192 | 0.486 |
| FAM218A | TMEM192 | ENSP00000427428 | ENSP00000305069 | Protein FAM218A; Family with sequence similarity 218 member A | Transmembrane protein 192 | 0.642 |
| FAM218A | TRIM60 | ENSP00000427428 | ENSP00000421142 | Protein FAM218A; Family with sequence similarity 218 member A | Tripartite motif containing 60; Belongs to the TRIM/RBCC family | 0.588 |
| FBXO27 | TMEM192 | ENSP00000292853 | ENSP00000305069 | F-box only protein 27; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex- type oligosaccharides; F-boxes other | Transmembrane protein 192 | 0.473 |
| KLHL34 | APBA2 | ENSP00000368813 | ENSP00000453293 | Kelch-like protein 34; Kelch like family member 34; BTB domain containing | Amyloid-beta A4 precursor protein-binding family A member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta; PDZ domain containing | 0.439 |
| KLHL34 | ELFN1 | ENSP00000368813 | ENSP00000456548 | Kelch-like protein 34; Kelch like family member 34; BTB domain containing | Protein ELFN1; Postsynaptic protein that regulates circuit dynamics in the central nervous system by modulating the temporal dynamics of interneuron recruitment. Specifically present in excitatory synapses onto oriens-lacunosum molecular (OLM) interneurons and acts as a regulator of presynaptic release probability to direct the formation of highly facilitating pyramidal-OLM synapses (By similarity). Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Fibronectin type III domain containing | 0.538 |
| KLHL34 | SMPX | ENSP00000368813 | ENSP00000368808 | Kelch-like protein 34; Kelch like family member 34; BTB domain containing | Small muscular protein; Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair; Deafness associated genes | 0.788 |
| KLHL34 | TMEM192 | ENSP00000368813 | ENSP00000305069 | Kelch-like protein 34; Kelch like family member 34; BTB domain containing | Transmembrane protein 192 | 0.529 |
| RARRES1 | TMEM192 | ENSP00000237696 | ENSP00000305069 | Retinoic acid receptor responder protein 1; Inhibitor of the cytoplasmic carboxypeptidase AGBL2, may regulate the alpha-tubulin tyrosination cycle | Transmembrane protein 192 | 0.672 |
| SLC35F6 | TMEM192 | ENSP00000345528 | ENSP00000305069 | Solute carrier family 35 member F6; Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter | Transmembrane protein 192 | 0.532 |
| SLC35F6 | TMEM55B | ENSP00000345528 | ENSP00000381102 | Solute carrier family 35 member F6; Involved in the maintenance of mitochondrial membrane potential in pancreatic ductal adenocarcinoma (PDAC) cells. Promotes pancreatic ductal adenocarcinoma (PDAC) cell growth. May play a role as a nucleotide-sugar transporter | Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4- bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3- monophosphate | 0.565 |
| SMPX | APBA2 | ENSP00000368808 | ENSP00000453293 | Small muscular protein; Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair; Deafness associated genes | Amyloid-beta A4 precursor protein-binding family A member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta; PDZ domain containing | 0.451 |
| SMPX | KLHL34 | ENSP00000368808 | ENSP00000368813 | Small muscular protein; Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair; Deafness associated genes | Kelch-like protein 34; Kelch like family member 34; BTB domain containing | 0.788 |
| SMPX | TMEM192 | ENSP00000368808 | ENSP00000305069 | Small muscular protein; Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair; Deafness associated genes | Transmembrane protein 192 | 0.466 |
| TMEM192 | APBA2 | ENSP00000305069 | ENSP00000453293 | Transmembrane protein 192 | Amyloid-beta A4 precursor protein-binding family A member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta; PDZ domain containing | 0.506 |
| TMEM192 | ELFN1 | ENSP00000305069 | ENSP00000456548 | Transmembrane protein 192 | Protein ELFN1; Postsynaptic protein that regulates circuit dynamics in the central nervous system by modulating the temporal dynamics of interneuron recruitment. Specifically present in excitatory synapses onto oriens-lacunosum molecular (OLM) interneurons and acts as a regulator of presynaptic release probability to direct the formation of highly facilitating pyramidal-OLM synapses (By similarity). Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Fibronectin type III domain containing | 0.486 |
