MSANTD4 protein (human) - STRING database

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MSANTD4

Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils (345 aa)

Predicted Functional Partners:

SLIRP

0.669

KBTBD3

0.643

TMEM60

0.640

CWF19L2

0.558

RNF111

0.535

ACN9

0.531

TMEM107

0.491

DHX15

0.476

MRPS15

0.447

ZDHHC4

0.440

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACN9	MSANTD4	ENSP00000414066	ENSP00000304713	Succinate dehydrogenase assembly factor 3, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1	Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils	0.531
CWF19L2	KBTBD3	ENSP00000282251	ENSP00000436262	CWF19-like protein 2; CWF19 like 2, cell cycle control; Belongs to the CWF19 family	Kelch repeat and BTB domain containing 3	0.680
CWF19L2	MSANTD4	ENSP00000282251	ENSP00000304713	CWF19-like protein 2; CWF19 like 2, cell cycle control; Belongs to the CWF19 family	Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils	0.558
DHX15	MSANTD4	ENSP00000336741	ENSP00000304713	Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns; Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily	Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils	0.476
KBTBD3	CWF19L2	ENSP00000436262	ENSP00000282251	Kelch repeat and BTB domain containing 3	CWF19-like protein 2; CWF19 like 2, cell cycle control; Belongs to the CWF19 family	0.680
KBTBD3	MSANTD4	ENSP00000436262	ENSP00000304713	Kelch repeat and BTB domain containing 3	Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils	0.643
MRPS15	MSANTD4	ENSP00000362208	ENSP00000304713	Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family	Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils	0.447
MRPS15	SLIRP	ENSP00000362208	ENSP00000450909	Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family	SRA stem-loop-interacting RNA-binding protein, mitochondrial; RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation	0.502
MRPS15	TMEM107	ENSP00000362208	ENSP00000314116	Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family	Transmembrane protein 107; Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern ventral and intermediate neuronal cell types (By similarity). During ciliogenesis regulates the ciliary transition zone localization of some MKS complex proteins	0.475
MSANTD4	ACN9	ENSP00000304713	ENSP00000414066	Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils	Succinate dehydrogenase assembly factor 3, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1	0.531
MSANTD4	CWF19L2	ENSP00000304713	ENSP00000282251	Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils	CWF19-like protein 2; CWF19 like 2, cell cycle control; Belongs to the CWF19 family	0.558
MSANTD4	DHX15	ENSP00000304713	ENSP00000336741	Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils	Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns; Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily	0.476
MSANTD4	KBTBD3	ENSP00000304713	ENSP00000436262	Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils	Kelch repeat and BTB domain containing 3	0.643
MSANTD4	MRPS15	ENSP00000304713	ENSP00000362208	Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils	Mitochondrial ribosomal protein S15; Belongs to the universal ribosomal protein uS15 family	0.447
MSANTD4	RNF111	ENSP00000304713	ENSP00000453872	Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils	E3 ubiquitin-protein ligase Arkadia; E3 ubiquitin-protein ligase. Required for mesoderm patterning during embryonic development (By similarity). Acts as an enhancer of the transcriptional responses of the SMAD2/SMAD3 effectors, which are activated downstream of BMP. Acts by mediating ubiquitination and degradation of SMAD inhibitors such as SMAD7, inducing their proteasomal degradation and thereby enhancing the transcriptional activity of TGF-beta and BMP. In addition to enhance transcription of SMAD2/SMAD3 effectors, also regulates their turnover by mediating their ubiquitination and [...]	0.535
MSANTD4	SLIRP	ENSP00000304713	ENSP00000450909	Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils	SRA stem-loop-interacting RNA-binding protein, mitochondrial; RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation	0.669
MSANTD4	TMEM107	ENSP00000304713	ENSP00000314116	Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils	Transmembrane protein 107; Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern ventral and intermediate neuronal cell types (By similarity). During ciliogenesis regulates the ciliary transition zone localization of some MKS complex proteins	0.491
MSANTD4	TMEM60	ENSP00000304713	ENSP00000257663	Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils	Transmembrane protein 60	0.640
MSANTD4	ZDHHC4	ENSP00000304713	ENSP00000379934	Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils	Probable palmitoyltransferase ZDHHC4; Zinc finger DHHC-type containing 4; Belongs to the DHHC palmitoyltransferase family	0.440
RNF111	MSANTD4	ENSP00000453872	ENSP00000304713	E3 ubiquitin-protein ligase Arkadia; E3 ubiquitin-protein ligase. Required for mesoderm patterning during embryonic development (By similarity). Acts as an enhancer of the transcriptional responses of the SMAD2/SMAD3 effectors, which are activated downstream of BMP. Acts by mediating ubiquitination and degradation of SMAD inhibitors such as SMAD7, inducing their proteasomal degradation and thereby enhancing the transcriptional activity of TGF-beta and BMP. In addition to enhance transcription of SMAD2/SMAD3 effectors, also regulates their turnover by mediating their ubiquitination and [...]	Myb/SANT-like DNA-binding domain-containing protein 4; Myb/SANT DNA binding domain containing 4 with coiled-coils	0.535

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