• Version:
  • 11.0 [archived version]
STRINGSTRING
DLC1 DLC1 ACOT11 ACOT11 PCTP PCTP ACOT12 ACOT12 COL4A3BP COL4A3BP STARD5 STARD5 STARD13 STARD13 SPG20 SPG20 PLEKHG1 PLEKHG1 STARD10 STARD10 GGA1 GGA1
"STARD5" - StAR-related lipid transfer protein 5 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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STARD5StAR-related lipid transfer protein 5; May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols (By similarity); StAR related lipid transfer domain containing (213 aa)    
Predicted Functional Partners:
PCTP
Phosphatidylcholine transfer protein; Catalyzes the transfer of phosphatidylcholine between membranes. Binds a single lipid molecule; StAR related lipid transfer domain containing (214 aa)
           
  0.800
STARD13
StAR-related lipid transfer protein 13; GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells (1113 aa)
           
  0.747
COL4A3BP
Collagen type IV alpha-3-binding protein; Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner; Pleckstrin homology domain containing (752 aa)
           
  0.742
ACOT12
Acyl-coenzyme A thioesterase 12; Hydrolyzes acetyl-CoA to acetate and CoA; Acyl-CoA thioesterases (555 aa)
           
  0.684
SPG20
Spartin; May be implicated in endosomal trafficking, or microtubule dynamics, or both. Participates in cytokinesis (666 aa)
           
  0.659
PLEKHG1
Pleckstrin homology and RhoGEF domain containing G1 (1385 aa)
           
  0.656
DLC1
Rho GTPase-activating protein 7; Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality (1528 aa)
           
  0.645
STARD10
START domain-containing protein 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes (291 aa)
           
  0.642
ACOT11
Acyl-coenzyme A thioesterase 11; Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates (607 aa)
           
  0.609
GGA1
ADP-ribosylation factor-binding protein GGA1; Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF- dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif (639 aa)
           
  0.586
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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