• Version:
  • 11.0 [archived version]
STRINGSTRING
CPA5 CPA5 CTRL CTRL CPB1 CPB1 CEL CEL PGA4 PGA4 CTRB2 CTRB2 CPA1 CPA1 CTRB1 CTRB1 CPA6 CPA6 MMP10 MMP10 TCN1 TCN1
"CTRB2" - Chymotrypsinogen B2 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
CTRB2Chymotrypsinogen B2; Belongs to the peptidase S1 family (263 aa)    
Predicted Functional Partners:
CPA1
Carboxypeptidase A1; Carboxypeptidase that catalyzes the release of a C- terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro; Belongs to the peptidase M14 family (419 aa)
     
 
  0.918
TCN1
Transcobalamin-1; Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach; Belongs to the eukaryotic cobalamin transport proteins family (433 aa)
         
  0.900
MMP10
Stromelysin-2; Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase; Belongs to the peptidase M10A family (476 aa)
         
    0.900
CTRB1
Chymotrypsinogen B1; Belongs to the peptidase S1 family (263 aa)
   
 
0.848
CPB1
M14 carboxypeptidases; Belongs to the peptidase M14 family (417 aa)
     
 
  0.748
CTRL
Chymotrypsin-like protease CTRL-1; Chymotrypsin like; Belongs to the peptidase S1 family (264 aa)
   
   
0.730
CPA6
Carboxypeptidase A6; May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II. Releases a C-terminal amino acid, with preference for large hydrophobic C-terminal amino acids and shows only very weak activity toward small amino acids and histidine; M14 carboxypeptidases (437 aa)
       
 
  0.727
CPA5
M14 carboxypeptidases; Belongs to the peptidase M14 family (436 aa)
     
 
  0.726
CEL
Bile salt-activated lipase; Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides; Belongs to the type-B carboxylesterase/lipase family (756 aa)
     
 
  0.725
PGA4
Pepsin A-4; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent; Belongs to the peptidase A1 family (388 aa)
           
  0.710
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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