node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCHCR1 | CDSN | ENSP00000379566 | ENSP00000365465 | Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation | Corneodesmosin; Important for the epidermal barrier integrity | 0.756 |
CCHCR1 | ETF1 | ENSP00000379566 | ENSP00000353741 | Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons | 0.592 |
CCHCR1 | MOG | ENSP00000379566 | ENSP00000366095 | Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation | Myelin-oligodendrocyte glycoprotein; Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell- cell communication; Belongs to the immunoglobulin superfamily. BTN/MOG family | 0.652 |
CCHCR1 | POU5F1 | ENSP00000379566 | ENSP00000259915 | Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation | POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5’-ATTTGCAT-3’). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency | 0.582 |
CCHCR1 | RMND5A | ENSP00000379566 | ENSP00000283632 | Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation | Protein RMD5 homolog A; Required for meiotic nuclear division 5 homolog A; CTLH complex | 0.551 |
CCHCR1 | RNF39 | ENSP00000379566 | ENSP00000244360 | Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation | RING finger protein 39; May play a role in prolonged long term-potentiation (LTP) maintenance; Ring finger proteins | 0.698 |
CCHCR1 | TCF19 | ENSP00000379566 | ENSP00000365433 | Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation | Transcription factor 19; Potential trans-activating factor that could play an important role in the transcription of genes required for the later stages of cell cycle progression; PHD finger proteins | 0.802 |
CCHCR1 | ZNF57 | ENSP00000379566 | ENSP00000303696 | Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation | Zinc finger protein 57; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.719 |
CDSN | CCHCR1 | ENSP00000365465 | ENSP00000379566 | Corneodesmosin; Important for the epidermal barrier integrity | Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation | 0.756 |
CDSN | MOG | ENSP00000365465 | ENSP00000366095 | Corneodesmosin; Important for the epidermal barrier integrity | Myelin-oligodendrocyte glycoprotein; Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell- cell communication; Belongs to the immunoglobulin superfamily. BTN/MOG family | 0.595 |
CDSN | POU5F1 | ENSP00000365465 | ENSP00000259915 | Corneodesmosin; Important for the epidermal barrier integrity | POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5’-ATTTGCAT-3’). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency | 0.639 |
CDSN | RMND5A | ENSP00000365465 | ENSP00000283632 | Corneodesmosin; Important for the epidermal barrier integrity | Protein RMD5 homolog A; Required for meiotic nuclear division 5 homolog A; CTLH complex | 0.541 |
CDSN | RNF39 | ENSP00000365465 | ENSP00000244360 | Corneodesmosin; Important for the epidermal barrier integrity | RING finger protein 39; May play a role in prolonged long term-potentiation (LTP) maintenance; Ring finger proteins | 0.689 |
CDSN | TCF19 | ENSP00000365465 | ENSP00000365433 | Corneodesmosin; Important for the epidermal barrier integrity | Transcription factor 19; Potential trans-activating factor that could play an important role in the transcription of genes required for the later stages of cell cycle progression; PHD finger proteins | 0.707 |
CDSN | ZNF57 | ENSP00000365465 | ENSP00000303696 | Corneodesmosin; Important for the epidermal barrier integrity | Zinc finger protein 57; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.676 |
ETF1 | CCHCR1 | ENSP00000353741 | ENSP00000379566 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons | Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation | 0.592 |
ETF1 | RNF39 | ENSP00000353741 | ENSP00000244360 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons | RING finger protein 39; May play a role in prolonged long term-potentiation (LTP) maintenance; Ring finger proteins | 0.531 |
ETF1 | TCF19 | ENSP00000353741 | ENSP00000365433 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons | Transcription factor 19; Potential trans-activating factor that could play an important role in the transcription of genes required for the later stages of cell cycle progression; PHD finger proteins | 0.542 |
ETF1 | ZNF57 | ENSP00000353741 | ENSP00000303696 | Eukaryotic peptide chain release factor subunit 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons | Zinc finger protein 57; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.604 |
MOG | CCHCR1 | ENSP00000366095 | ENSP00000379566 | Myelin-oligodendrocyte glycoprotein; Mediates homophilic cell-cell adhesion (By similarity). Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell- cell communication; Belongs to the immunoglobulin superfamily. BTN/MOG family | Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation | 0.652 |