ZNF280A protein (human) - STRING database

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ZNF280A

Zinc finger protein 280A; May function as a transcription factor (542 aa)

Predicted Functional Partners:

ZNF280B

0.927

PRAME

0.760

CDYL

0.717

CCDC71L

0.685

POM121L1P

0.679

RPL23A

0.649

GGTLC2

0.571

SCMH1

0.527

MOB3B

0.520

UBE2D3

0.485

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC71L	CDYL	ENSP00000430897	ENSP00000380718	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	Chromodomain Y-like protein; Isoform 2- Chromatin reader protein that recognizes and binds histone H3 trimethylated at ’Lys-9’, dimethylated at ’Lys- 27’ and trimethylated at ’Lys-27’ (H3K9me3, H3K27me2 and H3K27me3, respectively). Part of multimeric repressive chromatin complexes, where it is required for transmission and restoration of repressive histone marks, thereby preserving the epigenetic landscape. Required for chromatin targeting and maximal enzymatic activity of Polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing h [...]	0.526
CCDC71L	ZNF280A	ENSP00000430897	ENSP00000302855	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	Zinc finger protein 280A; May function as a transcription factor	0.685
CCDC71L	ZNF280B	ENSP00000430897	ENSP00000480958	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	Zinc finger protein 280B; May function as a transcription factor	0.567
CDYL	CCDC71L	ENSP00000380718	ENSP00000430897	Chromodomain Y-like protein; Isoform 2- Chromatin reader protein that recognizes and binds histone H3 trimethylated at ’Lys-9’, dimethylated at ’Lys- 27’ and trimethylated at ’Lys-27’ (H3K9me3, H3K27me2 and H3K27me3, respectively). Part of multimeric repressive chromatin complexes, where it is required for transmission and restoration of repressive histone marks, thereby preserving the epigenetic landscape. Required for chromatin targeting and maximal enzymatic activity of Polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing h [...]	Coiled-coil domain-containing protein 71L; Coiled-coil domain containing 71 like	0.526
CDYL	RPL23A	ENSP00000380718	ENSP00000389103	Chromodomain Y-like protein; Isoform 2- Chromatin reader protein that recognizes and binds histone H3 trimethylated at ’Lys-9’, dimethylated at ’Lys- 27’ and trimethylated at ’Lys-27’ (H3K9me3, H3K27me2 and H3K27me3, respectively). Part of multimeric repressive chromatin complexes, where it is required for transmission and restoration of repressive histone marks, thereby preserving the epigenetic landscape. Required for chromatin targeting and maximal enzymatic activity of Polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing h [...]	60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family	0.660
CDYL	UBE2D3	ENSP00000380718	ENSP00000349722	Chromodomain Y-like protein; Isoform 2- Chromatin reader protein that recognizes and binds histone H3 trimethylated at ’Lys-9’, dimethylated at ’Lys- 27’ and trimethylated at ’Lys-27’ (H3K9me3, H3K27me2 and H3K27me3, respectively). Part of multimeric repressive chromatin complexes, where it is required for transmission and restoration of repressive histone marks, thereby preserving the epigenetic landscape. Required for chromatin targeting and maximal enzymatic activity of Polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing h [...]	Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family	0.470
CDYL	ZNF280A	ENSP00000380718	ENSP00000302855	Chromodomain Y-like protein; Isoform 2- Chromatin reader protein that recognizes and binds histone H3 trimethylated at ’Lys-9’, dimethylated at ’Lys- 27’ and trimethylated at ’Lys-27’ (H3K9me3, H3K27me2 and H3K27me3, respectively). Part of multimeric repressive chromatin complexes, where it is required for transmission and restoration of repressive histone marks, thereby preserving the epigenetic landscape. Required for chromatin targeting and maximal enzymatic activity of Polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing h [...]	Zinc finger protein 280A; May function as a transcription factor	0.717
CDYL	ZNF280B	ENSP00000380718	ENSP00000480958	Chromodomain Y-like protein; Isoform 2- Chromatin reader protein that recognizes and binds histone H3 trimethylated at ’Lys-9’, dimethylated at ’Lys- 27’ and trimethylated at ’Lys-27’ (H3K9me3, H3K27me2 and H3K27me3, respectively). Part of multimeric repressive chromatin complexes, where it is required for transmission and restoration of repressive histone marks, thereby preserving the epigenetic landscape. Required for chromatin targeting and maximal enzymatic activity of Polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing h [...]	Zinc finger protein 280B; May function as a transcription factor	0.770
GGTLC2	POM121L1P	ENSP00000419751	ENSP00000481613	Gamma-glutamyltransferase light chain 2; Belongs to the gamma-glutamyltransferase family	annotation not available	0.556
GGTLC2	ZNF280A	ENSP00000419751	ENSP00000302855	Gamma-glutamyltransferase light chain 2; Belongs to the gamma-glutamyltransferase family	Zinc finger protein 280A; May function as a transcription factor	0.571
GGTLC2	ZNF280B	ENSP00000419751	ENSP00000480958	Gamma-glutamyltransferase light chain 2; Belongs to the gamma-glutamyltransferase family	Zinc finger protein 280B; May function as a transcription factor	0.530
MOB3B	ZNF280A	ENSP00000262244	ENSP00000302855	MOB kinase activator 3B; May regulate the activity of kinases; MOB kinase activators	Zinc finger protein 280A; May function as a transcription factor	0.520
POM121L1P	GGTLC2	ENSP00000481613	ENSP00000419751	annotation not available	Gamma-glutamyltransferase light chain 2; Belongs to the gamma-glutamyltransferase family	0.556
POM121L1P	PRAME	ENSP00000481613	ENSP00000445675	annotation not available	Melanoma antigen preferentially expressed in tumors; Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis; PRAME family	0.442
POM121L1P	ZNF280A	ENSP00000481613	ENSP00000302855	annotation not available	Zinc finger protein 280A; May function as a transcription factor	0.679
POM121L1P	ZNF280B	ENSP00000481613	ENSP00000480958	annotation not available	Zinc finger protein 280B; May function as a transcription factor	0.669
PRAME	POM121L1P	ENSP00000445675	ENSP00000481613	Melanoma antigen preferentially expressed in tumors; Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis; PRAME family	annotation not available	0.442
PRAME	ZNF280A	ENSP00000445675	ENSP00000302855	Melanoma antigen preferentially expressed in tumors; Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis; PRAME family	Zinc finger protein 280A; May function as a transcription factor	0.760
PRAME	ZNF280B	ENSP00000445675	ENSP00000480958	Melanoma antigen preferentially expressed in tumors; Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis; PRAME family	Zinc finger protein 280B; May function as a transcription factor	0.694
RPL23A	CDYL	ENSP00000389103	ENSP00000380718	60S ribosomal protein L23a; This protein binds to a specific region on the 26S rRNA; Belongs to the universal ribosomal protein uL23 family	Chromodomain Y-like protein; Isoform 2- Chromatin reader protein that recognizes and binds histone H3 trimethylated at ’Lys-9’, dimethylated at ’Lys- 27’ and trimethylated at ’Lys-27’ (H3K9me3, H3K27me2 and H3K27me3, respectively). Part of multimeric repressive chromatin complexes, where it is required for transmission and restoration of repressive histone marks, thereby preserving the epigenetic landscape. Required for chromatin targeting and maximal enzymatic activity of Polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing h [...]	0.660

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