node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BCAP29 | COG5 | ENSP00000368414 | ENSP00000297135 | B-cell receptor-associated protein 29; May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity); Belongs to the BCAP29/BCAP31 family | Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function; Belongs to the COG5 family | 0.840 |
BCAP29 | DUS4L | ENSP00000368414 | ENSP00000265720 | B-cell receptor-associated protein 29; May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity); Belongs to the BCAP29/BCAP31 family | tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs | 0.925 |
BCAP29 | GPR22 | ENSP00000368414 | ENSP00000302676 | B-cell receptor-associated protein 29; May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity); Belongs to the BCAP29/BCAP31 family | Probable G-protein coupled receptor 22; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.767 |
BCAP29 | PRKAR2B | ENSP00000368414 | ENSP00000265717 | B-cell receptor-associated protein 29; May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity); Belongs to the BCAP29/BCAP31 family | cAMP-dependent protein kinase type II-beta regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase | 0.776 |
CCDC174 | DNAJB9 | ENSP00000373304 | ENSP00000249356 | Coiled-coil domain-containing protein 174; Probably involved in neuronal development | DnaJ homolog subfamily B member 9; Involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Acts as a co-chaperone with an Hsp70 protein; DNAJ heat shock proteins | 0.595 |
CCDC174 | DNM1L | ENSP00000373304 | ENSP00000449089 | Coiled-coil domain-containing protein 174; Probably involved in neuronal development | Dynamin-1-like protein; Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane- associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptos [...] | 0.626 |
CCDC174 | GPR22 | ENSP00000373304 | ENSP00000302676 | Coiled-coil domain-containing protein 174; Probably involved in neuronal development | Probable G-protein coupled receptor 22; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.692 |
COG5 | BCAP29 | ENSP00000297135 | ENSP00000368414 | Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function; Belongs to the COG5 family | B-cell receptor-associated protein 29; May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity); Belongs to the BCAP29/BCAP31 family | 0.840 |
COG5 | DUS4L | ENSP00000297135 | ENSP00000265720 | Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function; Belongs to the COG5 family | tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs | 0.876 |
COG5 | GPR22 | ENSP00000297135 | ENSP00000302676 | Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function; Belongs to the COG5 family | Probable G-protein coupled receptor 22; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.752 |
COG5 | PRKAR2B | ENSP00000297135 | ENSP00000265717 | Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function; Belongs to the COG5 family | cAMP-dependent protein kinase type II-beta regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase | 0.741 |
DNAJB9 | CCDC174 | ENSP00000249356 | ENSP00000373304 | DnaJ homolog subfamily B member 9; Involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Acts as a co-chaperone with an Hsp70 protein; DNAJ heat shock proteins | Coiled-coil domain-containing protein 174; Probably involved in neuronal development | 0.595 |
DNAJB9 | DNM1L | ENSP00000249356 | ENSP00000449089 | DnaJ homolog subfamily B member 9; Involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Acts as a co-chaperone with an Hsp70 protein; DNAJ heat shock proteins | Dynamin-1-like protein; Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane- associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptos [...] | 0.542 |
DNAJB9 | GPR22 | ENSP00000249356 | ENSP00000302676 | DnaJ homolog subfamily B member 9; Involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Acts as a co-chaperone with an Hsp70 protein; DNAJ heat shock proteins | Probable G-protein coupled receptor 22; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.635 |
DNM1L | CCDC174 | ENSP00000449089 | ENSP00000373304 | Dynamin-1-like protein; Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane- associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptos [...] | Coiled-coil domain-containing protein 174; Probably involved in neuronal development | 0.626 |
DNM1L | DNAJB9 | ENSP00000449089 | ENSP00000249356 | Dynamin-1-like protein; Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane- associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptos [...] | DnaJ homolog subfamily B member 9; Involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Acts as a co-chaperone with an Hsp70 protein; DNAJ heat shock proteins | 0.542 |
DNM1L | GPR22 | ENSP00000449089 | ENSP00000302676 | Dynamin-1-like protein; Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane- associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptos [...] | Probable G-protein coupled receptor 22; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.645 |
DUS4L | BCAP29 | ENSP00000265720 | ENSP00000368414 | tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs | B-cell receptor-associated protein 29; May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity); Belongs to the BCAP29/BCAP31 family | 0.925 |
DUS4L | COG5 | ENSP00000265720 | ENSP00000297135 | tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs | Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function; Belongs to the COG5 family | 0.876 |
DUS4L | GPR22 | ENSP00000265720 | ENSP00000302676 | tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs | Probable G-protein coupled receptor 22; Orphan receptor; G protein-coupled receptors, Class A orphans | 0.808 |