ABHD15 protein (human) - STRING database

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ABHD15

Protein ABHD15; Abhydrolase domain containing 15 (468 aa)

Predicted Functional Partners:

HSPA2

0.670

SPATA2L

0.598

PDE3B

0.594

NAGS

0.570

FAM193B

0.563

ABHD17B

0.553

GDPD1

0.551

HPCAL4

0.549

PTMA

0.544

ABHD16B

0.526

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABHD15	ABHD16B	ENSP00000302657	ENSP00000358932	Protein ABHD15; Abhydrolase domain containing 15	Protein ABHD16B; Abhydrolase domain containing 16B; Belongs to the AB hydrolase superfamily. ABHD16 family	0.526
ABHD15	ABHD17B	ENSP00000302657	ENSP00000366240	Protein ABHD15; Abhydrolase domain containing 15	Protein ABHD17B; Abhydrolase domain containing 17B; Belongs to the AB hydrolase superfamily. ABHD17 family	0.553
ABHD15	FAM193B	ENSP00000302657	ENSP00000422131	Protein ABHD15; Abhydrolase domain containing 15	Protein FAM193B; Family with sequence similarity 193 member B; Belongs to the FAM193 family	0.563
ABHD15	GDPD1	ENSP00000302657	ENSP00000284116	Protein ABHD15; Abhydrolase domain containing 15	Lysophospholipase D GDPD1; Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF), lysophosphatidylethanolamine (lyso-PE) and lysophosphatidylcholine (lyso-PC). May be involved in bioactive N-acylethanolamine biosynthesis. Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine	0.551
ABHD15	HPCAL4	ENSP00000302657	ENSP00000361935	Protein ABHD15; Abhydrolase domain containing 15	Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing	0.549
ABHD15	HSPA2	ENSP00000302657	ENSP00000378199	Protein ABHD15; Abhydrolase domain containing 15	Heat shock-related 70 kDa protein 2; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis [...]	0.670
ABHD15	NAGS	ENSP00000302657	ENSP00000293404	Protein ABHD15; Abhydrolase domain containing 15	N-acetylglutamate synthase, mitochondrial; Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPSI) activity; Belongs to the acetyltransferase family	0.570
ABHD15	PDE3B	ENSP00000302657	ENSP00000282096	Protein ABHD15; Abhydrolase domain containing 15	cGMP-inhibited 3’,5’-cyclic phosphodiesterase B; Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis; Phosphodiesterases	0.594
ABHD15	PTMA	ENSP00000302657	ENSP00000344547	Protein ABHD15; Abhydrolase domain containing 15	Prothymosin alpha; Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections	0.544
ABHD15	SPATA2L	ENSP00000302657	ENSP00000289805	Protein ABHD15; Abhydrolase domain containing 15	Spermatogenesis-associated protein 2-like protein; Spermatogenesis associated 2 like	0.598
ABHD16B	ABHD15	ENSP00000358932	ENSP00000302657	Protein ABHD16B; Abhydrolase domain containing 16B; Belongs to the AB hydrolase superfamily. ABHD16 family	Protein ABHD15; Abhydrolase domain containing 15	0.526
ABHD16B	ABHD17B	ENSP00000358932	ENSP00000366240	Protein ABHD16B; Abhydrolase domain containing 16B; Belongs to the AB hydrolase superfamily. ABHD16 family	Protein ABHD17B; Abhydrolase domain containing 17B; Belongs to the AB hydrolase superfamily. ABHD17 family	0.586
ABHD17B	ABHD15	ENSP00000366240	ENSP00000302657	Protein ABHD17B; Abhydrolase domain containing 17B; Belongs to the AB hydrolase superfamily. ABHD17 family	Protein ABHD15; Abhydrolase domain containing 15	0.553
ABHD17B	ABHD16B	ENSP00000366240	ENSP00000358932	Protein ABHD17B; Abhydrolase domain containing 17B; Belongs to the AB hydrolase superfamily. ABHD17 family	Protein ABHD16B; Abhydrolase domain containing 16B; Belongs to the AB hydrolase superfamily. ABHD16 family	0.586
FAM193B	ABHD15	ENSP00000422131	ENSP00000302657	Protein FAM193B; Family with sequence similarity 193 member B; Belongs to the FAM193 family	Protein ABHD15; Abhydrolase domain containing 15	0.563
GDPD1	ABHD15	ENSP00000284116	ENSP00000302657	Lysophospholipase D GDPD1; Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF), lysophosphatidylethanolamine (lyso-PE) and lysophosphatidylcholine (lyso-PC). May be involved in bioactive N-acylethanolamine biosynthesis. Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine	Protein ABHD15; Abhydrolase domain containing 15	0.551
GDPD1	HPCAL4	ENSP00000284116	ENSP00000361935	Lysophospholipase D GDPD1; Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF), lysophosphatidylethanolamine (lyso-PE) and lysophosphatidylcholine (lyso-PC). May be involved in bioactive N-acylethanolamine biosynthesis. Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine	Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing	0.510
HPCAL4	ABHD15	ENSP00000361935	ENSP00000302657	Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing	Protein ABHD15; Abhydrolase domain containing 15	0.549
HPCAL4	GDPD1	ENSP00000361935	ENSP00000284116	Hippocalcin-like protein 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation; EF-hand domain containing	Lysophospholipase D GDPD1; Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines. Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF), lysophosphatidylethanolamine (lyso-PE) and lysophosphatidylcholine (lyso-PC). May be involved in bioactive N-acylethanolamine biosynthesis. Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine	0.510
HSPA2	ABHD15	ENSP00000378199	ENSP00000302657	Heat shock-related 70 kDa protein 2; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis [...]	Protein ABHD15; Abhydrolase domain containing 15	0.670

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