node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BMP2K | FAM84B | ENSP00000334836 | ENSP00000302578 | BMP-2-inducible protein kinase; May be involved in osteoblast differentiation | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | 0.600 |
BMP2K | REPS1 | ENSP00000334836 | ENSP00000392065 | BMP-2-inducible protein kinase; May be involved in osteoblast differentiation | RalBP1-associated Eps domain-containing protein 1; May coordinate the cellular actions of activated EGF receptors and Ral-GTPases; EF-hand domain containing | 0.977 |
C10orf76 | FAM84B | ENSP00000359050 | ENSP00000302578 | UPF0668 protein C10orf76; Chromosome 10 open reading frame 76 | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | 0.577 |
CTNNA1 | FAM84B | ENSP00000304669 | ENSP00000302578 | Catenin alpha-1; Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and [...] | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | 0.785 |
CXorf36 | ELAC2 | ENSP00000381086 | ENSP00000337445 | Deleted in autism-related protein 1; Chromosome X open reading frame 36 | Zinc phosphodiesterase ELAC protein 2; Zinc phosphodiesterase, which displays mitochondrial tRNA 3’-processing endonuclease activity. Involved in tRNA maturation, by removing a 3’-trailer from precursor tRNA | 0.510 |
CXorf36 | FAM84B | ENSP00000381086 | ENSP00000302578 | Deleted in autism-related protein 1; Chromosome X open reading frame 36 | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | 0.582 |
CXorf36 | POU5F1B | ENSP00000381086 | ENSP00000419298 | Deleted in autism-related protein 1; Chromosome X open reading frame 36 | Putative POU domain, class 5, transcription factor 1B; Shows weak transcriptional activator activity; POU class homeoboxes and pseudogenes | 0.444 |
ELAC2 | CXorf36 | ENSP00000337445 | ENSP00000381086 | Zinc phosphodiesterase ELAC protein 2; Zinc phosphodiesterase, which displays mitochondrial tRNA 3’-processing endonuclease activity. Involved in tRNA maturation, by removing a 3’-trailer from precursor tRNA | Deleted in autism-related protein 1; Chromosome X open reading frame 36 | 0.510 |
ELAC2 | FAM84B | ENSP00000337445 | ENSP00000302578 | Zinc phosphodiesterase ELAC protein 2; Zinc phosphodiesterase, which displays mitochondrial tRNA 3’-processing endonuclease activity. Involved in tRNA maturation, by removing a 3’-trailer from precursor tRNA | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | 0.721 |
FAM84B | BMP2K | ENSP00000302578 | ENSP00000334836 | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | BMP-2-inducible protein kinase; May be involved in osteoblast differentiation | 0.600 |
FAM84B | C10orf76 | ENSP00000302578 | ENSP00000359050 | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | UPF0668 protein C10orf76; Chromosome 10 open reading frame 76 | 0.577 |
FAM84B | CTNNA1 | ENSP00000302578 | ENSP00000304669 | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | Catenin alpha-1; Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and [...] | 0.785 |
FAM84B | CXorf36 | ENSP00000302578 | ENSP00000381086 | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | Deleted in autism-related protein 1; Chromosome X open reading frame 36 | 0.582 |
FAM84B | ELAC2 | ENSP00000302578 | ENSP00000337445 | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | Zinc phosphodiesterase ELAC protein 2; Zinc phosphodiesterase, which displays mitochondrial tRNA 3’-processing endonuclease activity. Involved in tRNA maturation, by removing a 3’-trailer from precursor tRNA | 0.721 |
FAM84B | HRASLS | ENSP00000302578 | ENSP00000264735 | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | 0.691 |
FAM84B | POU5F1B | ENSP00000302578 | ENSP00000419298 | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | Putative POU domain, class 5, transcription factor 1B; Shows weak transcriptional activator activity; POU class homeoboxes and pseudogenes | 0.586 |
FAM84B | REPS1 | ENSP00000302578 | ENSP00000392065 | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | RalBP1-associated Eps domain-containing protein 1; May coordinate the cellular actions of activated EGF receptors and Ral-GTPases; EF-hand domain containing | 0.706 |
FAM84B | UROD | ENSP00000302578 | ENSP00000246337 | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III | 0.766 |
FAM84B | ZNF572 | ENSP00000302578 | ENSP00000319305 | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | Zinc finger protein 572; May be involved in transcriptional regulation; Zinc fingers C2H2-type | 0.575 |
HRASLS | FAM84B | ENSP00000264735 | ENSP00000302578 | Phospholipid-metabolizing enzyme A-C1; Exhibits calcium-independent phospholipase activity towards phosphatidylcholine (PC) and phosphatidylethanolamine (PE). Also shows acyltransferase activities, transferring an acyl group of PCs to the amino group of PEs and the hydroxyl group of lyso PCs; HRAS like suppressor family | Protein FAM84B; Family with sequence similarity 84 member B; Belongs to the FAM84 family | 0.691 |