• Version:
  • 11.0 [archived version]
STRINGSTRING
ZCWPW1 ZCWPW1 TMEM120A TMEM120A CCDC129 CCDC129 HSF2BP HSF2BP C1QTNF4 C1QTNF4 ILDR2 ILDR2 CLASRP CLASRP LRIG1 LRIG1 B4GALNT4 B4GALNT4 MXRA7 MXRA7 CCDC9 CCDC9
"C1QTNF4" - Complement C1q tumor necrosis factor-related protein 4 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
C1QTNF4Complement C1q tumor necrosis factor-related protein 4; May act as a pro-inflammatory cytokine, that induces the activation of NF-kappa-B signaling pathway and up-regulates IL6 production; C1q and TNF related (329 aa)    
Predicted Functional Partners:
B4GALNT4
N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N’-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans; Belongs to the chondroitin N- acetylgalactosaminyltransferase family (1039 aa)
     
   
  0.756
ILDR2
Immunoglobulin-like domain-containing receptor 2; May be involved in lipid homeostasis and ER stress pathways (639 aa)
     
   
  0.739
MXRA7
Matrix-remodeling-associated protein 7; Matrix remodeling associated 7 (204 aa)
           
  0.573
TMEM120A
Transmembrane protein 120A; Necessary for efficient adipogenesis; Belongs to the TMEM120 family (343 aa)
           
  0.516
CLASRP
CLK4-associating serine/arginine rich protein; Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family (By similarity); Belongs to the splicing factor SR family (674 aa)
           
  0.515
HSF2BP
Heat shock factor 2-binding protein; May be involved in modulating HSF2 activation in testis. Inhibits BNC1 transcriptional activity during spermatogenesis, probably by sequestering it in the cytoplasm (By similarity); Armadillo-like helical domain containing (334 aa)
           
  0.508
CCDC9
Coiled-coil domain containing 9 (531 aa)
           
  0.500
LRIG1
Leucine-rich repeats and immunoglobulin-like domains protein 1; Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation; I-set domain containing (1093 aa)
           
  0.492
CCDC129
Coiled-coil domain containing 129 (1062 aa)
           
  0.481
ZCWPW1
Zinc finger CW-type and PWWP domain containing 1 (648 aa)
           
  0.472
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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